NCT05174351

Beta-blocker Discontinuation in Heart Failure With Preserved Ejection Fraction

Effect of Beta-blocker Discontinuation on Functional Capacity and Cardiac Hemodynamics in Patients With Heart Failure With Preserved Ejection Fraction

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: UConn Health · Academic / Other
• Sex: All
• Age: 50 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This is a prospective pilot study to evaluate changes before and 4 weeks after beta-blocker withdrawal in 30 HFpEF patients.

Detailed description

This is a prospective pilot study to evaluate changes before and 4 weeks(+/- 1 week) after beta-blocker withdrawal in 30 HFpEF patients. The study involves 2 visits that are 4 weeks apart. The first study visit will occur at a standard of care clinic visit and the second visit will be a research visit to fill out questionnaires and perform the limited echocardiogram. No long term follow up beyond the 2nd visit.

Conditions

• Heart Failure With Preserved Ejection Fraction

Interventions

Type	Name	Description
OTHER	beta blocker discontinuation	beta blocker discontinuation

Timeline

• Start date: 2021-12-20
• Primary completion: 2027-11-01
• Completion: 2027-11-01
• First posted: 2021-12-30
• Last updated: 2025-09-29

Locations

1 site across 1 country: United States