Clinical Trials Directory

Trials / Withdrawn

WithdrawnNCT05146154

Impact of Obesity on the Pharmacokinetics of Imipenem-Relebactam in ICU Patients

Status
Withdrawn
Phase
Phase 4
Study type
Interventional
Enrollment
0 (actual)
Sponsor
University of Illinois at Chicago · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study is an open-label, multiple-dose pharmacokinetic study of imipenem-relebactam conducted in 12 non-infected, obese ICU patients.

Conditions

Interventions

TypeNameDescription
DRUGImipenem/Cilastatin/Relebactam 1.25gImipenem/cilastatin/relebactam is a combination beta-lactam/beta-lactamase inhibitor antimicrobial marketed under the brand name Recarbrio and the approved dose is 1.25g Q6h in patients with normal renal function. The individual components of this agent must be administered together and cannot be separated. Therefore, this constitutes only one intervention. Each subject will receive at least 2 doses of study drug.

Timeline

Start date
2023-01-01
Primary completion
2023-06-01
Completion
2024-01-01
First posted
2021-12-06
Last updated
2024-11-27

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05146154. Inclusion in this directory is not an endorsement.