NCT05143710

The Clinical and Prognostic Features of PRES

The Features of Clinical Imaging, Disease Severity and Pregnancy Outcomes in Posterior Reversible Encephalopathy Syndrome With Preeclampsia or Eclampsia

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 354 (actual)
• Sponsor: Dunjin Chen · Academic / Other
• Sex: Female
• Age: 16 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine the features of clinical imaging, disease severity and pregnancy outcomes in posterior reversible encephalopathy syndrome with preeclampsia or eclampsia.

Detailed description

The investigators retrospectively collected data (General information, clinical data, biochemical indicators, imaging features, and pregnancy outcome) from pregnant woman diagnosed with PRES with preeclampsia or eclampsia to analyze features of clinical imaging, disease severity and pregnancy outcomes during 2012 to 2021.Then, the investigators grouped all the patients into early onset group and late onset PE group according to gestational weeks to analyze differences of clinical imaging. Finally, the investigators grouped all the patients into good pregnancy outcomes group and poor pregnancy outcomes group according to diagnostic criteria, including the incidence of stillbirth and premature birth, to analyze differences of clinical imaging .

Conditions

• Posterior Reversible Encephalopathy Syndrome
• Pregnancy Outcomes
• Preeclampsia
• Eclampsia

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	PRES in PE or E	patients diagnosed with posterior reversible encephalopathy syndrome with preeclampsia or eclampsia

Timeline

• Start date: 2020-10-01
• Primary completion: 2022-01-31
• Completion: 2022-01-31
• First posted: 2021-12-03
• Last updated: 2022-03-02

Locations

1 site across 1 country: China