NCT05122520

Hydrogen and Methane Breath Test Questionnaire

A Questionnaire to Identify Predictive Symptoms and Risk Factors for Hydrogen and Methane Breath Testing Outcomes

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,040 (actual)
• Sponsor: The Functional Gut Clinic · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: —

Summary

Lactulose HMBT and Glucose HMBT are simple non-invasive tests to assess whether imbalances in gut bacteria may be contributing to troublesome tummy symptoms. These imbalances in gut bacteria include small intestinal bacterial overgrowth (SIBO) and excessive methane production. Recently there has been a lot of work to done by experts in the field, to ensure that performance and interpretation of these tests are standardised, to help improve the clinical utility of these investigations. Although there is a lot of information currently available demonstrating the risk factors and symptoms associated with these conditions, there is a lack of data demonstrating the factors that might lead to a positive test according to these new parameters. This study aims to collect data on symptoms and medical history, in patients referred for lactulose and glucose HMBT in order further improve the effectiveness of this test in the future.

Conditions

• Small Intestinal Bacterial Overgrowth

Interventions

Type	Name	Description
OTHER	Questionnaire	The HMBT-Q is a 26-item questionnaire, split into four main sections: food related symptoms; general digestive symptoms; extra-intestinal symptoms and co-morbidities and Medication and onset.

Timeline

• Start date: 2021-02-10
• Primary completion: 2023-03-26
• Completion: 2023-04-26
• First posted: 2021-11-16
• Last updated: 2023-06-02

Locations

1 site across 1 country: United Kingdom