| Not Yet Recruiting | A Trial of a Multi-Component Nutritional Supplement in Hydrogen-Dominant Small Intestinal Bacterial Overgrowth NCT07215676 | National University of Natural Medicine | N/A |
| Not Yet Recruiting | Methane and Hydrogen Breath Test for the Diagnosis of Small Intestinal Bacterial Overgrowth NCT06483360 | Shanghai Jiao Tong University School of Medicine | — |
| Recruiting | The Safety And Efficacy Of A Probiotic Intervention On Lactulose Hydrogen Breath Test-Positive Patients And Re NCT06317441 | Nimble Science Ltd. | N/A |
| Recruiting | Pilot Feasibility Study of Fecal Microbiota Transplant for the Treatment of Small Intestinal Bacterial Overgro NCT05967871 | McMaster Children's Hospital | Phase 1 |
| Recruiting | Evaluating the Effect Of Rifaximin on the Gut Microbiota and Metabolome in SIBO Using CapScan® NCT06298409 | Envivo Bio Inc | Phase 1 |
| Completed | The Low FODMAP Diet in Individuals With Small Intestinal Bacterial Overgrowth (SIBO) NCT07424313 | Warsaw University of Life Sciences | N/A |
| Completed | Gut Microbiome-Metabolome Profiling in H. Pylori-SIBO Comorbidity NCT07122284 | Zhongshan Hospital (Xiamen), Fudan University | — |
| Completed | Therapeutic Effect of Olive Leaf Tea on SIBO NCT05915767 | University of Veterinary and Animal Sciences, Lahore - Pakistan | N/A |
| Completed | The Efficacy of Probiotics as an Adjunct to Treatment of SIBO With Rifaximin NCT06223685 | Pomeranian Medical University Szczecin | N/A |
| Completed | Clinical Study of Fecal Microbiota Transplantation in the Treatment of Small Intestinal Bacterial Overgrowth ( NCT06162702 | Shanghai 10th People's Hospital | N/A |
| Withdrawn | Rifaximin's Effect on Covert Hepatic Encephalopathy With SIBO and Gastrointestinal Dysmotility NCT04244877 | MetroHealth Medical Center | Phase 3 |
| Unknown | Feasibility of a New Diagnostic Device to Assess Small Intestinal Dysbiosis in Routine Clinical Setting. NCT04910815 | Atmo Biosciences Pty Ltd | N/A |
| Unknown | Rifaximin Therapy vs Low FODMAP Diet In IBS NCT04841980 | University of Malaya | Phase 4 |
| Completed | High-fat Diet (HFD) and Small Intestinal Microbiome NCT07019142 | Insel Gruppe AG, University Hospital Bern | N/A |
| Completed | Hydrogen and Methane Breath Test Questionnaire NCT05122520 | The Functional Gut Clinic | — |
| Terminated | Effect of a Probiotic Formula on Reducing SIBO in IBS Patients NCT04316806 | AB Biotics, SA | N/A |
| Unknown | Efficacy of AEMCOLO (Rifamycin SV MMX) in the Treatment of Small Intestinal Bacterial Overgrowth (SIBO) NCT04501380 | Bradley Connor | Phase 2 |
| Completed | Intestinal Adsorbent and Breath Gas Levels NCT04492839 | Dr Anthony Hobson | N/A |
| Unknown | The Small Intestine Bacterial Overgrowth Study Pilot NCT03588845 | Canadian Scleroderma Research Group | N/A |
| Unknown | Comparative Assessment of Radioisotope Glucose and Breath Test NCT04499742 | Augusta University | — |
| Completed | Small Intestinal Bacterial Overgrowth in Critically Ill Patients NCT05765994 | University of Ioannina | — |
| Unknown | Characteristic of Intestinal Flora in Male Elderly With Small Intestinal Bacterial Overgrowth NCT03659175 | Chinese PLA General Hospital | — |
| Withdrawn | Novel Supplement-based Therapy for the Treatment of Small Intestinal Bacterial Overgrowth NCT03420976 | Atrium Innovations | EARLY_Phase 1 |
| Terminated | Effycacy of Rifaximin on Reverse Minimal Hepatic Encephalopathy and Elimation Small Intestinal Bacterial NCT02439307 | Coordinación de Investigación en Salud, Mexico | N/A |
| Completed | Treating Bacterial Overgrowth in Parkinson's Disease NCT02470780 | University of Cincinnati | Phase 2 / Phase 3 |
| Completed | Bifidobacterium Infantis M-63 Improves Mental Health in Irritable Bowel Syndrome Developed After a Major Flood NCT03318614 | Universiti Sains Malaysia | Phase 2 / Phase 3 |
| Completed | Effectiveness of Saccharomyces Boulardii for Gastrointestinal Bacterial-overgrowth in Systemic Sclerosis NCT03692299 | Coordinación de Investigación en Salud, Mexico | Phase 4 |
| Completed | SIBO & SIFO After Colectomy NCT03216239 | Augusta University | — |
| Unknown | Antibiotic Treatment Trial for Small Intestinal Bacterial Overgrowth NCT02458781 | San Antonio Military Medical Center | Phase 4 |
| Recruiting | Indiana University Gastrointestinal Motility Diagnosis Registry NCT04506593 | Indiana University | — |
| Completed | Use of SBI in IBS Subjects Following a Successful Treatment of Small Intestinal Bacterial Overgrowth NCT02251483 | Cedars-Sinai Medical Center | N/A |
| Completed | SIBO, Immune Activation, and FGIDs in Children NCT02872961 | The University of Texas Health Science Center, Houston | — |
| Enrolling By Invitation | Small Intestinal Bacterial Overgrowth: A Prospective Registry NCT01822470 | Indiana University | — |
| Completed | Clinical Utility of Breath Tests in GI NCT03261856 | Augusta University | — |
| Completed | Gulf War Digestive Health Study NCT00680836 | US Department of Veterans Affairs | N/A |
| Completed | Does Small Intestinal Bacterial Overgrowth Contribute to Functional Dyspepsia NCT00956397 | Henry C. Lin, MD | N/A |
| Completed | Is Chronic Abdominal Pain in Pediatric Patients Due to Small Intestinal Bacterial Overgrowth? NCT00619970 | Children's Hospital Los Angeles | N/A |