NCT05112146

Effects of Whey Protein Pre-meals on Post-prandial Glucose

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Société des Produits Nestlé (SPN) · Industry
• Sex: All
• Age: 40 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The aim of this project was to determine if an administration of either 10 g of whey protein isolate or 10 g of whey protein microgels 30 or 10 min before a standard meal could reduce postprandial glucose response in obese subjects.

Detailed description

Monocentric, controlled, randomized, open, complete cross-over study design where participants will take 2 test products or water (negative control) at 2 different time points. The targeted population will be 16 completely healthy males and females at risk for pre-diabetes. Primary objective: To quantify the effects of whey protein pre-meals administrated at 30 or 10 min before a meal on post-prandial glucose in the interstitial tissue, as compared to water as negative control. Secondary objective: To compare glucose response of the different pre-meals (water, whey protein isolate, whey protein micelles).

Conditions

• Prediabetic State

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Whey protein isolate	Oral administration
DIETARY_SUPPLEMENT	Whey protein microgel	Oral administration
DIETARY_SUPPLEMENT	Water	Oral administration

Timeline

• Start date: 2018-08-20
• Primary completion: 2018-08-29
• Completion: 2018-08-29
• First posted: 2021-11-08
• Last updated: 2021-11-08

Locations

1 site across 1 country: Switzerland