Trials / Unknown
UnknownNCT05104619
Spectroscopic Analysis of Tongue Tumor Samples.
Prospective Analysis of Tumor Tissues From the Oral Cavity by SpiderMassTM Spectroscopy
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 14 (estimated)
- Sponsor
- Centre Hospitalier Universitaire, Amiens · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
In squamous cell carcinoma of the tongue, complete surgical resection of the tumor generally represents the primary treatment strategy. Among factors determining the disease prognostic, the surgical margins status is essential for the continued management of the patient, with or without complementary therapies. Generally, surgical margins are defined using visual and tactile elements. Unfortunately, in 15 to 30 percent of cases, they are defined as positive after histopathological examination, on average 5 to 7 days post-surgery. Techniques have recently been developed to analyze the cancerous and non-cancerous nature of tissues, using the spectral properties of tumor cells. SpiderMass™ is an instrument equipped with a probe for tissue micro-sampling and real-time molecular profile analysis. It is thus ultimately a tool for anatomopathological decision support, for diagnosis and prognosis of the disease. Used in the operating room, SpiderMass™ could also become an innovative surgical tool to precisely define cancerous areas in situ and the margins status in intraoperative conditions. Based on the principle of artificial intelligence, the SpiderMass™ machine must initially learn to recognize pathological tissues versus healthy. This project aims to accomplish this first phase of machine learning for squamous cell carcinoma of the tongue.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | tongue surgery | In squamous cell carcinoma of the tongue, complete surgical resection of the tumor |
Timeline
- Start date
- 2021-10-01
- Primary completion
- 2023-10-01
- Completion
- 2023-10-01
- First posted
- 2021-11-03
- Last updated
- 2023-02-08
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT05104619. Inclusion in this directory is not an endorsement.