Trials / Completed
CompletedNCT05098600
The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic
The Epidemiology, Management and Associated Conditions in Alopecia Areata in Czech Republic: A University-clinic-based Cross-sectional and Cohort Study
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 123 (actual)
- Sponsor
- Faculty Hospital Kralovske Vinohrady · Other Government
- Sex
- All
- Age
- —
- Healthy volunteers
- Not accepted
Summary
The study series consists of three studies with the aim to assess the incidence, prevalence, risk factors, comorbidities and management of patients with alopecia areata in Czech Republic based on the patients and registry of a dermatology clinic of a metropolitan hospital.
Detailed description
The first study will aim to identify the incidence and prevalence of alopecia areata in the dermatology clinic of a metropolitan teaching hospital between 1/1/2011 and 31/12/2020 The second study will assess (1) the epidemiology of autoimmune and atopic diseases in patients with alopecia areata, (2) the presence of possible risk factors responsible for the onset/relapse/exacerbation of alopecia areata, (3) the levels of vitamin D and various autoantibodies,particularly thyroid autoantibodies and (4) the variety, duration, efficacy and safety profile of treatment modalities used in our hospital for the management of alopecia areata from 15/10/2021 to 14/10/2022. The third study will monitor the monthly oscillations of vitamin D and thyroid-autoantibodies of patients with new-onset/relasping or exacerbating alopecia areata for six months, between 15/10/2021-14/10/2022 in order to observe if changes in levels of vitamin D and thyroid-antiantibodies are associated with severity and prognosis (worsening or improvement) of alopecia areata
Conditions
- Alopecia Areata
- Alopecia Totalis
- Alopecia Universalis
- Alopecia Areata (& Ophiasis)
- Alopecia Barbae
- Alopecia Diffuse
- Autoimmune Diseases
- Autoimmune Hyperthyroidism
- Autoimmune Hypothyroidism
- Diabetes Mellitus, Type 1
- Ulcerative Colitis
- Inflammatory Bowel Diseases
- Crohn Disease
- Rheumatoid Arthritis
- Down Syndrome
- Atopic Dermatitis
- Atopic Asthma
- Atopic Rhinitis
- Vitiligo
- Psoriasis
- Ankylosing Spondylitis
- Multiple Sclerosis
- Lupus Erythematosus
- COVID-19 Pandemic
- Vaccine Reaction
- Infections
- Anemia, Pernicious
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Exposure of interest | Common autoimmune and atopic conditions consist of atopic dermatitis, allergic rhinitis, asthma, Crohn's disease, ulcerative colitis, Celiac disease, Pernicious anaemia, Type 1 diabetes, Autoimmune thyroiditis (Hashimoto's thyroiditis, Grave's disease, atrophic, unspecified), rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, polymyalgia rheumatica, Systemic lupus erythematosus, Sjogren syndrome, psoriasis, vitiligo, Multiple sclerosis |
Timeline
- Start date
- 2021-10-15
- Primary completion
- 2022-10-14
- Completion
- 2022-12-20
- First posted
- 2021-10-28
- Last updated
- 2024-12-03
Locations
1 site across 1 country: Czechia
Source: ClinicalTrials.gov record NCT05098600. Inclusion in this directory is not an endorsement.