NCT05095090

Study of Hospitalised Patients With Acute Respiratory Conditions

Observational Cohort Study of Hospitalised Patients With Acute Respiratory Conditions

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 130 (actual)
• Sponsor: University of Leicester · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Accepted

Summary

This observational study aim to characterise patients admitted to hospital with an acute respiratory condition, or acute worsening of their chronic lung condition. This will enable identification of predictors of future risk, as well as develop potential interventions targets.

Detailed description

This will be an observational cohort study, recruiting patients who have been admitted to hospital with an acute respiratory condition. This can include exacerbation of an existing chronic lung disease such as asthma, COPD, interstitial lung disease, bronchiectasis and pleural disease, or contracting an acute illness including pulmonary embolism, pneumonia, or any other respiratory infection. The patients will be screened and recruited whilst still hospitalised and followed up for one year after discharge. The participants will undergo a baseline study visit while in hospital, with the option to have further follow up visits (up to three occasions) in the following year to assess clinical recovery. The participants will be offered the choice to undertake the follow up assessments via any of the following routes: * a telephone consultation or * a face to face visit either in the Biomedical Research Centre (BRC) or * during a research visit from another ethically approved study or * during routine clinical follow up organised by the hospital clinical team. The participants can choose not to attend any further follow up visits after discharge. Any planned clinical follow-up arranged by the hospital team will occur according to clinical needs. If the participant is re-admitted during the 12 months after enrolment, assessments identical to the baseline visit can be repeated. A final remote visit will be carried out at 12 months post-discharge (+/- 1 month) to collect data about health care utilisation (e.g. hospitalisation rate, length of stay in hospital, death rate, antibiotic/steroid prescriptions) from both primary and secondary healthcare records. The participants are not required to attend this final visit as data will be collected remotely.

Conditions

• Acute Respiratory Disease
• COPD Exacerbation Acute
• Asthma
• Pneumonia

Timeline

• Start date: 2022-02-02
• Primary completion: 2024-04-30
• Completion: 2024-04-30
• First posted: 2021-10-27
• Last updated: 2023-05-10

Locations

1 site across 1 country: United Kingdom