NCT05094362

Operant Conditioning of Spinal Reflexes Training System--Reflex Operant Down Conditioning

Operant Conditioning of Spinal Reflexes to Enhance Motor Function Recovery After Spinal Cord Injury

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 25 (estimated)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to validate the capacity of a reflex training system to change the size of the targeted reflex. For this, the researchers are recruiting 25 individuals with chronic incomplete SCI who have spasticity in the leg to participate in the reflex training procedure. The study involves approximately 45 visits with a total study duration of about 6 months.

Conditions

• Spinal Cord Injuries
• Neurological Injury
• Paralysis
• Spasticity, Muscle

Interventions

Type	Name	Description
BEHAVIORAL	Spinal Reflex Operant Down Conditioning	This is a training intervention in which people with a spinal cord injury are trained to reduce the activity of a certain spinal reflex. By decreasing this reflex, individuals decrease hyperactivity in the reflex and can reduce spasticity.

Timeline

• Start date: 2023-08-23
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2021-10-26
• Last updated: 2025-09-09

Locations

2 sites across 1 country: United States