NCT05064007

Sound and Music for Mild Cognitive Impairment

The Power of Sound and Music Interventions for Older Adults With Mild Cognitive Impairment

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: Johns Hopkins University · Academic / Other
• Sex: All
• Age: 50 Years – 95 Years
• Healthy volunteers: Accepted

Summary

Emerging studies in humans found that 40 Hz sound induces neural gamma oscillation and enhanced cognitive function in older adults with and without Alzheimer's Disease. We will compare a 40 Hz music intervention to both 40 Hz sound and music alone in a clinical cohort of older adults with mild cognitive impairment.

Conditions

• Mild Cognitive Impairment

Interventions

Type	Name	Description
BEHAVIORAL	A: 40 Hz music	The participant will listen to the 40 Hz music playlist one hour each day, 5 days a week for 4 weeks
BEHAVIORAL	B: 40 Hz sound	The participant will listen to the 40 Hz sound playlist one hour each day, 5 days a week for 4 weeks
BEHAVIORAL	C: Preferred music	The participant will listen to the preferred music playlist one hour each day, 5 days a week for 4 weeks

Timeline

• Start date: 2022-02-01
• Primary completion: 2024-04-03
• Completion: 2025-04-03
• First posted: 2021-10-01
• Last updated: 2025-08-29
• Results posted: 2025-08-29

Locations

1 site across 1 country: United States