NCT05053087

A Study to Compare the Effectiveness of Adductor Canal Pain Catheters Following Total Knee Arthroplasty

A Three-Arm, Double-Blinded, Randomized Controlled Trial Comparing the Efficacy of Adductor Canal Pain Catheters Following Total Knee Arthroplasty

• Status: Completed
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years – 89 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research is to study how well the adductor canal pain catheters works after a total knee arthroplasty or replacement of the knee joint. The catheter works by using either an intermittent bolus injection to provide a large dose of medication or continuous infusion of pain medicine, ropivacaine 0.2%, compared to a single-shot adductor canal block.

Conditions

• Osteoarthritis, Knee

Interventions

Type	Name	Description
DRUG	Ropivacaine Continuous Infusion	0.2% continuous infusion 6mL/hr
DRUG	Ropivacaine Intermittent Bolus	0.2% intermittent bolus infusion 8mL every 2 hours
DRUG	Placebo	Saline filled catheter

Timeline

• Start date: 2022-04-13
• Primary completion: 2023-02-27
• Completion: 2023-02-27
• First posted: 2021-09-22
• Last updated: 2024-02-22
• Results posted: 2024-02-22

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study