NCT05023122

The Effect of Oral Vitamin D Supplements on Fusion Outcome in Patients Receiving Elective Lumbar Spinal Fusion

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: Show Chwan Memorial Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The process of bony fusion is a dynamic bone remodeling process and a variety of risk factors have been identified to contribute to pseudoarthrosis.Vitamin D deficiency has been reported to be associated with more pseudoarthrosis, prolonged time to fusion, and poorer spine function and quality of life after spinal fusion.However, as the review article presented, it lacks high-quality evidence to investigate the role of vitamin D supplements in spinal fusion. Therefore, this randomized controlled trial aimed to evaluate the effectiveness of oral vitamin D supplements on fusion outcomes in patients receiving elective lumbar spinal fusion.

Conditions

• Vitamin D
• Spinal Fusion
• Lumbar Spine Disease

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	vitamin D3	vitamin D3 (cholecalciferol) 800 IU QD
DIETARY_SUPPLEMENT	calcium	calcium citrate 600 mg QD

Timeline

• Start date: 2016-01-01
• Primary completion: 2017-12-31
• Completion: 2018-12-31
• First posted: 2021-08-26
• Last updated: 2021-08-26

Locations

1 site across 1 country: Taiwan