NCT05018325

Assessing Effect of Withdrawal Time on Adenoma Detection Rate for Screening Colonoscopy

Assessing Effect of Withdrawal Time on Adenoma Detection Rate for Screening Colonoscopy: A Randomized Tandem Study

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 32 (actual)
• Sponsor: Washington University School of Medicine · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

The investigators' null hypothesis is that a withdrawal time of 9 to 10 minutes is non-inferior to a withdrawal time of 12 minutes or greater. Thus, the goal of this tandem design trial is to compare the additional diagnostic yield (# of missed lesions) for withdrawal times exceeding 10 minutes for screening/surveillance colonoscopies. Although withdrawal times longer than the standard 6-minute recommendation have been shown to be beneficial, there is limited prospective evidence investigating the benefit or lack thereof for withdrawal times greater than 9-10 minutes.

Conditions

• Colon Cancer
• Rectal Cancer
• Colorectal Cancer

Interventions

Type	Name	Description
PROCEDURE	Colonoscopy with 6 minute withdrawal	Withdrawal time will be determined using a digital stopwatch by the nursing staff.
PROCEDURE	Colonoscopy 9 minute withdrawal	Withdrawal time will be determined using a digital stopwatch by the nursing staff.
PROCEDURE	Colonoscopy 12 minute withdrawal	Withdrawal time will be determined using a digital stopwatch by the nursing staff.

Timeline

• Start date: 2021-08-30
• Primary completion: 2022-08-19
• Completion: 2022-08-19
• First posted: 2021-08-24
• Last updated: 2022-08-31

Locations

1 site across 1 country: United States