NCT05014893

Neural Mechanisms of Cognitive Assessment and Rehabilitation for Cognitive Decline

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: National Research Center for Rehabilitation Technical Aids · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This study investigates the neural mechanisms of cognitive function decline, cognitive assessment methods for subjects with mild cognitive dysfunction (Mild cognitive impairment, MCI, or cognitive decline milder than MCI), and the approaches used to improve and restore cognitive function.

Detailed description

Cognitive assessment tools are used to assess cognitive function of subjects in different cities. Functional and structural MRI and EEG are applied to investigate the neural mechanisms of cognitive function decline and effects of methods to improve and restore cognitive function.

Conditions

• Mild Cognitive Impairment (MCI)
• Subjective Cognitive Decline (SCD)
• Aging
• Healthy

Interventions

Type	Name	Description
COMBINATION_PRODUCT	multi-modal targeted intervention (e.g., cognitive training, exercise, games)	The Intervention group will be given recommended interventions tailored to individuals based on their risks (e.g., physical exercise programs, cognitive training, dietary advice, control of blood pressure and cholesterol, healthy diet, control obesity, stop smoking,reduce alcohol excess)

Timeline

• Start date: 2021-08-06
• Primary completion: 2026-12-31
• Completion: 2026-12-31
• First posted: 2021-08-20
• Last updated: 2025-05-22

Locations

1 site across 1 country: China