NCT05010889

Quality of Life After POEM for Achalasia

Health-Related Quality of Life After Peroral Endoscopic Myotomy for Patients With Achalasia

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 200 (estimated)
• Sponsor: First Affiliated Hospital, Sun Yat-Sen University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Achalasia is an esophageal motility disorder, characterized by insufficient lower esophageal sphincter relaxation and loss of esophageal peristalsis. Patients with achalasia experience distressing gastrointestinal symptoms, including dysphagia, reflux and chest pain, which lead to weight loss and malnutrition. Undoubtedly, health-related quality of life can be significantly diminished in patients with achalasia. At present, POEM has become one of the standard therapies for achalasia. Limited studies have focused on the patient's quality of life before and after POEM. The present study aimed to assess the changes in quality of life of patients with achalasia using the validated achalasia severity questionnaire (ASQ) and the short form (SF)-36 scale.

Conditions

• Esophageal Achalasia

Interventions

Type	Name	Description
PROCEDURE	Peroral endoscopic myotomy (POEM)	POEM is performed as previously described by Inoue et al (Endoscopy 2010), including four main steps mucosal incision, submucosal tunneling, myotomy and mucosal entry closure.

Timeline

• Start date: 2021-09-01
• Primary completion: 2022-12-31
• Completion: 2022-12-31
• First posted: 2021-08-18
• Last updated: 2021-08-18

Locations

1 site across 1 country: China