NCT05006443

Staging Classification of Severe Tricuspid Regurgitation Using Novel Cardiac Imaging Techniques

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 75 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years – 99 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this research is to assess the severity of tricuspid regurgitation (a disorder in which the tricuspid valve in the heart does not close tight enough) using cardiac magnetic resonance imaging (MRI).

Detailed description

40 patients with moderate or more TR on echocardiography will undergo CMR/MRE with contrast to assess TR severity, and the associated extra-valvular cardiac and liver abnormalities as shown in the flow diagram below. Patients will continue their clinical management by their primary physicians as per the standards of care. 1-year follow up will be conducted via phone to inquire about patient's vital status (dead/alive), symptoms and hospitalizations.

Conditions

• Tricuspid Regurgitation

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Cardiac Magnetic Resonance	a non-invasive assessment to determine severity of tricuspid regurgitation

Timeline

• Start date: 2022-01-14
• Primary completion: 2023-12-12
• Completion: 2025-04-30
• First posted: 2021-08-16
• Last updated: 2025-05-13

Locations

1 site across 1 country: United States