NCT04996693

On Dose Efficiency of Modern CT-scanners in Chest Scans

On Dose Efficiency of Modern CT-scanners in Chest Scans- a Prospective, Randomized Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 958 (actual)
• Sponsor: University Hospital Augsburg · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

CT scans of the chest / thorax are of great importance both in the initial diagnosis and in the follow-up of pulmonary or thoracic diseases. As an example, CT angiography of the pulmonary arteries (CTPA) is worldwide considered to be gold standard test in patients with a suspicion for pulmonary embolism. The aim of this study is to measure and compare dose efficiency of modern CT scanners for unenhanced and contrast-enhanced scan protocols of the chest/thorax. Patients who are referred for a CT of the chest/thorax will be randomly assigned to one of the three CT scanners currently in use at our institution.

Conditions

• Pneumonia
• Lung Cancer
• Pulmonary Embolism
• Pulmonary Disease
• Aortic Stenosis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Imaging on Scanner with Spectral Imaging Capabilities	Patients will undergo imaging on a modern CT scanner with spectral imaging capabilities. A dose neutral spectral acquisition mode will routinely be used. Contrast material protocol and scan ranges are similar in all three arms.
DIAGNOSTIC_TEST	CT Scan using an Energy-Integrating Detector CT (128 slice MDCT)	Patients will undergo imaging on a modern 128-slice CT scanner (Siemens Healthineers) with energy-integrating detector and without spectral acquisition mode. Contrast material protocol and scan ranges are similar in all three arms.
DIAGNOSTIC_TEST	CT Scan using an Energy-Integrating Detector CT (20-slice MDCT)	Patients will undergo imaging on a modern 20-slice CT scanner (Siemens Healthineers) with energy-integrating detector and without spectral acquisition mode. Contrast material protocol and scan ranges are similar in all three arms.

Timeline

• Start date: 2021-10-07
• Primary completion: 2023-05-31
• Completion: 2023-05-31
• First posted: 2021-08-09
• Last updated: 2023-11-22

Locations

1 site across 1 country: Germany