NCT04982341

HFNC and Prone Positioning in Awake Patients With Severe COVID-19

Effectiveness of High-flow Nasal Cannula and Prone Positioning in Awake Patients With COVID-19 and Severe Acute Respiratory Failure

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 120 (actual)
• Sponsor: Hôpital Universitaire Fattouma Bourguiba · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: —

Summary

The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF.

Detailed description

The investigators evaluate the effects of High-flow nasal cannula (HFNC) in association with prone in patients with Covid-19 severe ARF. All patients with ARF related to Covid-19 and admitted to the ICU are turned in prone position whenever tolerated, while receiving oxygenation with HFNC. Outcomes of interest are the rate of success or failure (defined as the need for intubation and mechanical ventilation)

Conditions

• Hypoxemic Respiratory Failure

Interventions

Type	Name	Description
PROCEDURE	prone position	patients are returned from prone to supine position while receiving oxygenation through HFNC

Timeline

• Start date: 2020-09-02
• Primary completion: 2021-03-03
• Completion: 2021-03-03
• First posted: 2021-07-29
• Last updated: 2021-07-29

Locations

1 site across 1 country: Tunisia