NCT04976686

Low Carbohydrate Small Intestine Study

Studying the Impact of a Low Carbohydrate Diet on the Small Intestinal Microbiota

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: Insel Gruppe AG, University Hospital Bern · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The investigators will recruit probands with a ileo- or colostoma that are otherwise in good general health and analyse the stomal fluids for their microbiota composition. Sampling will be performed over a time span of 28 days, after 14 days probands will modify their base-line diet to a low carbohydrate diet.

Detailed description

Additionally to stoma fluids which will be analyzed for their microbiota composition the investigators will also collect skin samples to analyze for microbiota composition and urine to analyze for metabolite composition. Low carbohydrate diet will allow for consumption of 80g complex carbohydrates per day, simple sugars will have to be avoided completely

Conditions

• Diet, Healthy

Interventions

Type	Name	Description
OTHER	Diet modification	Participants will reduce their carbohydrate consumption to 80g daily

Timeline

• Start date: 2021-11-17
• Primary completion: 2024-11-30
• Completion: 2024-11-30
• First posted: 2021-07-26
• Last updated: 2024-12-09

Locations

1 site across 1 country: Switzerland