NCT04972513

Impact of E-cigarette Use on the Body

The Emerging Adulthood Health Project

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 182 (actual)
• Sponsor: Ohio State University Comprehensive Cancer Center · Academic / Other
• Sex: All
• Age: 15 Years – 25 Years
• Healthy volunteers: Accepted

Summary

This study examines how electronic (e)-cigarette use impacts the body, by studying both users and non-users of e-cigarettes. Early evidence indicates that e-cig users experience adverse health effects. Results of this study may help policy-makers develop standards for different types of tobacco.

Detailed description

PRIMARY OBJECTIVE: Examine the short-term impacts of vaping on pulmonary and respiratory outcomes. OUTLINE: Current e-cigarette users will vape their own e-cigarette device ad libitum for 30 minutes; non-users will watch a neutral video for 30 minutes. Before and after the 30 minute vaping \[video\] session, participants will undergo the following assessments: computer-based spirometry testing, nitric oxide breath testing, airwave oscillometry, and an assessment of endothelial function. Participants will also undergo collection of blood.

Conditions

• Cigarette Smoking-Related Carcinoma

Interventions

Type	Name	Description
PROCEDURE	Biospecimen Collection	Undergo collection of blood
PROCEDURE	Nitric Oxide Breath Test	Undergo nitric oxide breath testing
PROCEDURE	Oscillometry	Undergo airwave oscillometry
PROCEDURE	Spirometry	Undergo spirometry
OTHER	Survey Administration	Complete survey
PROCEDURE	Endothelial function	Endothelial function will be assessed with the EndoPAT device, which measures changes in pressure from sensors placed on the fingertip

Timeline

• Start date: 2021-07-22
• Primary completion: 2022-06-29
• Completion: 2026-12-31
• First posted: 2021-07-22
• Last updated: 2026-03-23

Locations

1 site across 1 country: United States