NCT04958629

A Prospective Cohort Study on Familial Hypercholesterolemia in Health Examination Population

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 318 (estimated)
• Sponsor: Peking University Third Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To determine the prevalence and the prognosis in a corhort of patients with familial hypercholesterolemia (FH).

Detailed description

This study aims to achieve the following goals through prospective cohort study and statistical analysis: (1) to determine the prevalence of familial hypercholesterolemia (FH) in healthy people with hypercholesterolemia.（2) Compared with non FH population, the relative risk of atherosclerotic cardiovascular disease (ASCVD) in FH patients in China was calculated, and the risk prediction model of ASCVD in FH patients was constructed by using biochemical results, imaging data, biomarkers and other indicators.（3) To evaluate the benefits of different lipid-lowering strategies for FH patients in China.（4) To analyze the gene carriers of FH patients in China.

Conditions

• Familial Hypercholesterolemia

Interventions

Type	Name	Description
OTHER	familial hypercholesterolemia	Among the selected patients with hyperlipidemia, those who met the diagnostic criteria of FH were included in the study cohort as FH group.

Timeline

• Start date: 2021-10-01
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2021-07-12
• Last updated: 2021-09-20