NCT04958005

Salivary Interleukin-32, Interleukin-10, Interleukin-6 and Tumor Necrosis Factor-alpha Levels in Children

Evaluation of Salivary Interleukin-32, Interleukin-10, Interleukin-6 and Tumor Necrosis Factor-alpha Levels in Children With Early Childhood Caries.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 58 (actual)
• Sponsor: Aydin Adnan Menderes University · Academic / Other
• Sex: All
• Age: 3 Years – 70 Months
• Healthy volunteers: —

Summary

This study aimed to evaluate the levels of interleukin 10, interleukin 6, interleukin 32 and tumor necrosis factor-alpha (TNF-α) in saliva of children with early childhood caries.

Detailed description

Fifty six children ( 28 with early childhood caries and 28 without early childhood caries ; age range 3-6 years) will be recruited for the study. Probing pocket depth (PPD), gingival index (GI) and plaque index (PI) will be recorded and saliva samples will be collected. Interleukin-32, Interleukin-10, Interleukin-6 and TNF-α will be analyzed in saliva samples by ELISA.

Conditions

• Early Childhood Caries

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	ELISA	Enzim linked immunoabsorbant assay

Timeline

• Start date: 2021-07-01
• Primary completion: 2021-08-30
• Completion: 2021-09-30
• First posted: 2021-07-12
• Last updated: 2021-10-21

Locations

1 site across 1 country: Turkey (Türkiye)