| Not Yet Recruiting | Vertical Dimension Changes After Bioflx vs Stainless Steel Crowns in Primary Molars NCT07523776 | Cairo University | N/A |
| Not Yet Recruiting | Study of Obstacles and Barriers to Changing Risky Eating Behaviors in Families of Children With Severe Early C NCT07377240 | University Hospital, Clermont-Ferrand | N/A |
| Not Yet Recruiting | Effectiveness and Acceptability of SDF Compared to ART for the Management of Early Childhood Caries NCT06786975 | Universidad de La Frontera | N/A |
| Recruiting | Oral Health Intervention for Caregivers of Children Presenting for Dental Surgery NCT07220850 | University of Illinois at Chicago | N/A |
| Recruiting | Oropharyngeal Candidiasis (OPC) and S-ECC NCT05761197 | Temple University | — |
| Recruiting | Oral Health and Dental Caries Prevention Intervention for Children in Romania NCT06441500 | University of Medicine and Pharmacy "Victor Babes" Timisoara | N/A |
| Active Not Recruiting | Arresting Early Childhood Caries With a Silver Diamine Fluoride Gel NCT06241261 | The University of Hong Kong | Phase 2 |
| Unknown | Comparing Controlled Flow Delivery Dentapen® Technique to Traditional Syringes NCT05959642 | Cairo University | N/A |
| Recruiting | A Tele-detection and Referral Pathways Model for Early Childhood Caries Control NCT06019884 | University of Alexandria | N/A |
| Active Not Recruiting | Salivary Cystatin S Levels in a Group of Egyptian Children NCT05716867 | Cairo University | — |
| Unknown | Effectiveness of Strengthened Anticipatory Guidance Used in the MOH Malaysia Infant Oral Health Care Programme NCT06000293 | Universiti Sains Malaysia | N/A |
| Completed | Effect of Optimized Behavioural Intervention Using The Multi-Phase Optimization Strategy (MOST). NCT04923581 | Merna Ihab | N/A |
| Completed | The Anticariogenic Effect of Silver Diamine Fluoride and Sodium Fluoride Varnish NCT06316323 | Universiti Teknologi Mara | Phase 1 |
| Recruiting | Povidone Iodine Efficacy Study NCT05272254 | University of Rochester | Phase 2 |
| Unknown | Technology-Based Parent School Program NCT05370989 | Gazi University | N/A |
| Unknown | Clinical Evaluation of High Viscosity Glass Ionomer Strip Crowns in Primary Maxillary Incisors NCT05838469 | Hacettepe University | N/A |
| Unknown | Oral Health-Related Quality of Life of Early Childhood Caries Using Silver Diamine Fluoride Versus Drill and F NCT05337449 | Cairo University | N/A |
| Withdrawn | Happy Teeth for Hopi Tots: Cultural Adaptation of an Oral Health Entertainment-Education Intervention NCT05297526 | Northern Arizona University | N/A |
| Unknown | Leptin, Adiponectin, FRAP and Tac in Patients With Early Childhood Caries NCT05352841 | University of Novi Sad | — |
| Completed | Silver Diamine Fluoride Versus Sodium Fluoride Varnish With Parental Behavior Modification in Arresting Early NCT05761041 | Alexandria University | Phase 3 |
| Completed | Effectiveness of Nano-silver Fluoride and Silver Diamine Fluoride for Arresting Early Childhood Caries NCT05255913 | Alexandria University | N/A |
| Completed | Silver Diamine Fluoride(SDF) Versus SDF Combined With Sodium Fluoride Varnish in the Arrest of Early Childhood NCT05642494 | Alexandria University | Phase 3 |
| Unknown | Treatment of Early Childhood Caries Using Silver Diammine Fluoride and Sodium Fluoride Tricalciumphosphate and NCT05772039 | Universiti Sains Malaysia | Phase 4 |
| Unknown | Clinical Analysis of a Risk-graded and Comprehensive Intervention for Early-childhood-caries NCT05260216 | Beijing Friendship Hospital | N/A |
| Completed | Effect of Application Time of 38% Silver Diamine Fluoride Solution on Arresting Dental Caries in Preschool Chi NCT04655430 | The University of Hong Kong | Phase 2 / Phase 3 |
| Unknown | Clinical Efficiency and Treatment Failure of Hall Versus SDF Techniques in the Management of Carious Primary M NCT04765904 | Cairo University | N/A |
| Completed | Salivary Interleukin-32, Interleukin-10, Interleukin-6 and Tumor Necrosis Factor-alpha Levels in Children NCT04958005 | Aydin Adnan Menderes University | — |
| Unknown | Clinical Efficiency and Child's Behavior of Hall Versus SDF Techniques in the Management of Carious Primary Mo NCT04737057 | Cairo University | N/A |
| Terminated | Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project NCT04556175 | Northern Arizona University | N/A |
| Completed | Acceptance and Efficacy of a Digital Application Among Parents to Control Early Childhood Caries NCT05515510 | University Medicine Greifswald | N/A |
| Unknown | HBM for Empowering Parental Toothbrushing and Sugar Intake Control NCT04665219 | The University of Hong Kong | N/A |
| Unknown | Parental Acceptance and Perception of Silver Diamine FlouridApplication Among A Sample of Egyptian Children. NCT04218955 | Cairo University | — |
| Completed | Early Childhood Caries in Jordanian Children NCT05748054 | King Abdullah University Hospital | N/A |
| Completed | A Clinical Trial of Silver Diamine Fluoride to Arrest Early Childhood Caries in Young Children NCT04054635 | University of Manitoba | N/A |
| Unknown | Knowledge, Practice and Attitude of Paediatricians Regarding Early Childhood Caries NCT04003129 | Cairo University | — |
| Unknown | Effect of Three Types of Fluoride Varnish in Preventing Early Childhood Caries NCT04274569 | The University of Hong Kong | N/A |
| Completed | Investigation of Supragingival Plaque Microbiome in Early Childhood Caries NCT04456335 | Trakya University | — |
| Completed | Knowledge and Behavior Toward Early Childhood Caries NCT03693443 | October University for Modern Sciences and Arts | — |
| Completed | Silver Diamine Fluoride Effectiveness Versus Atraumatic Restorative Treatment in Arresting ECC NCT04514094 | Hams Hamed Abdelrahman | N/A |
| Completed | Antimicrobial Effect OF Propolis Administrated Through Two Different Vehicles In High Caries Risk Children NCT03812315 | Nourhan M.Aly | Phase 2 |
| Completed | Obesity and Caries in Young South Asian Children: A Common Risk Factor Approach NCT03077425 | Albert Einstein College of Medicine | N/A |
| Completed | The Caries-arresting Effect of Incorporating fTCP to NaF Varnish Applied Following AgNO3 in Preschool Children NCT03423797 | The University of Hong Kong | Phase 3 |
| Completed | Caregiver-Child Interaction and Health Behaviors NCT03162822 | NYU Langone Health | N/A |
| Completed | Effectiveness Fluoride Varnishes in Children With Early Childhood Caries NCT03625310 | Merve Erkmen Almaz | N/A |
| Completed | Clinical Performance of Composite Coronal Build -Up in Mutilated Primary Incisors: 3 Years Results NCT04758221 | Cairo University | N/A |
| Completed | Evaluation of Remineralizing Efficacy of Combination Varnishes on White Spot Lesions in ECC Children NCT03360266 | Indira Gandhi Institute of Dental Science | N/A |
| Completed | A Telephone-based Case-management Intervention for Caries Prevention in Children With Severe Early Childhood C NCT02487043 | Karolinska Institutet | N/A |
| Completed | Effectiveness of Dental Caries Arrest Treatment in Primary Teeth Using AgNO3 Followed by NaF Varnish NCT02019160 | The University of Hong Kong | Phase 3 |
| Active Not Recruiting | Cohort Zero Caries NCT02578966 | Hospital Nossa Senhora da Conceicao | N/A |
| Completed | Effectiveness of SDF in Arresting Dental Caries in Preschool Children NCT02385474 | The University of Hong Kong | Phase 3 |
| Completed | Midazolam Efficacy for Sedating Preschoolers Undergoing Dental Treatment NCT01795222 | Universidade Federal de Goias | Phase 4 |
| Unknown | Preventing Early Childhood Caries in Indigenous Children: the Baby Teeth Talk Study NCT02151916 | University of Toronto | Phase 3 |
| Completed | Atraumatic Restorative Treatment (ART) in Early Childhood Caries (ECC) NCT03756025 | Hospital Nossa Senhora da Conceicao | N/A |