Trials / Active Not Recruiting
Active Not RecruitingNCT04946734
Effectivity and Safety of PFO Closure vs Medicine in Alleviating Migraine
Effectivity and Safety of PFO Closure vs Medicine in Alleviating Migraine （SPRING）: a Multicenter, Random, Case Control Study
- Status
- Active Not Recruiting
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 440 (estimated)
- Sponsor
- Guangdong Provincial People's Hospital · Academic / Other
- Sex
- All
- Age
- 16 Years – 60 Years
- Healthy volunteers
- Not accepted
Summary
Effectivity and safety of PFO closure vs medicine in alleviating migraine （SPRING）: a multicenter, random, case control study
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | PFO closure device | Device PFO closure. |
| DRUG | Aspirin and clopidogrel | Aspirin 100mg qd for 6 months and clopidogrel 75mg qd administered for 1month after device implanted. |
| DRUG | Triptans | If migraine recurred, Triptans would be administered during the acute phase. |
Timeline
- Start date
- 2021-08-12
- Primary completion
- 2025-09-06
- Completion
- 2025-09-06
- First posted
- 2021-07-01
- Last updated
- 2025-03-12
Locations
21 sites across 1 country: China
Source: ClinicalTrials.gov record NCT04946734. Inclusion in this directory is not an endorsement.