NCT04921202

Metabolic Syndrome and Degenerative Meniscus Lesions Related Knee Function

First Affiliated Hospital of Jinzhou Medical Universtiy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 180 (actual)
• Sponsor: The First People's Hospital of Jingzhou · Academic / Other
• Sex: All
• Age: 35 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Studies have suggested that Obese patients with metabolic syndrome(MetS)were correlated with knee joint degeneration and osteoarthritis. However, no studies demonstrate the relationship between obese patients with metabolic syndrome and degenerate meniscus lesions and its knee function.The aim is to detect the correlation between obese patients with metabolic syndrome and degenerate meniscus injuries.

Detailed description

Obese patients with metabolic syndrome(MetS)were correlated with knee joint degeneration and osteoarthritis. However, no studies demonstrate the relationship between patients with metabolic syndrome and degenerate meniscus lesions or knee function. Participants were recruited from First Affiliated Hospital of Jinzhou Medical University. 100 BMI\<24 people without Metabolic syndrome volunteers aged between 35-70 years old and 80 Metabolic syndrome patients with BMI\>27 were included in the study. Obese patients with MetS were assessed knee function and degenerate meniscus tears verified by magnetic resonance imaging. And patients with a mild or no osteoarthritis with Kellgren and Lawrence grade\<2 verified by X ray. We tested the relationship between metabolic syndrome and degenerate meniscus lesions. Obese patients with MetS and volunteers were detected by Mcmurry's test and MRI image to measure degeneration grade of meniscus tears. Number of MetS components were accounted and the knee function KOOS, IKDC score or degenerate meniscus tears were analyzed.

Conditions

• Metabolic Syndrome
• Meniscus Lesion
• Obesity, Abdominal
• Knee Arthritis

Interventions

Type	Name	Description
OTHER	Metabolic syndrome and meniscus injuries	Metabolic syndrome

Timeline

• Start date: 2017-06-01
• Primary completion: 2020-03-25
• Completion: 2021-03-01
• First posted: 2021-06-10
• Last updated: 2021-06-10

Locations

1 site across 1 country: China