NCT04913935

Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA

Investigation of Parameters of Trapeziometacarpal Joint Configuration and Tenar Muscles in Patients With TMC OA

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 24 (actual)
• Sponsor: Hacettepe University · Academic / Other
• Sex: Female
• Age: 35 Years – 75 Years
• Healthy volunteers: Accepted

Summary

In this study, investigators aimed to investigate the morphometric parameters tenar muscles and joint configuration in patients with trapeziometacarpal osteoarthritis (TMC OA) osteoarthritis stages, thenar muscle parameters, radial subluxation rate, functional level and hand dexterity.

Detailed description

Patients diagnosed with trapeziometacarpal osteoarthritis and healthy subjects will be included in the study. Thickness and cross-sectional area measurements of the thenar muscles of the patient and healthy volunteers will be performed by using Shimadzu SDU 1200-Pro ultrasound system with an 8-10 MHz linear probe. To improve the image quality and to avoid muscle compression, water immersion ultrasonography will be preferred and the hands will be positioned in a water-filled plastic container. The thenar muscles will be imaged in hands of each subject. In this study, poster-anterior radiographic imaging will be performed. The osteoarthritis stage will be determined on the radiographic image. Three different measurements will be performed on radiography: radial subluxation of the first metacarpal base (RS), articular width (AW) of the first metacarpal, and the distance between the ulnar articular facet of the trapezium and the ulnar edge of the metacarpal (U). RS / AW ratio will be calculated. Because TMC OA caused pain and affect performance, especially during grip activities in the osteoarthritis and control groups will be tested. Grip strength will also be measured.

Conditions

• Thumb Osteoarthritis
• Muscle Atrophy or Weakness

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Muscle-Skeleton Ultrasonography	postero-anterior radiography

Timeline

• Start date: 2019-09-05
• Primary completion: 2019-12-28
• Completion: 2020-01-15
• First posted: 2021-06-04
• Last updated: 2021-06-04

Locations

1 site across 1 country: Turkey (Türkiye)