| Not Yet Recruiting | Thumb Base Osteoarthritis: Ultrasound-guided Platelet-rich Plasma Versus Placebo Injection NCT07491302 | Goed Medisch Centrum | Phase 2 |
| Not Yet Recruiting | ICF-Based Biopsychosocial Assessment With AI-Assisted Profile Prediction: Trapeziometacarpal Osteoarthritis Mo NCT07458971 | Hacettepe University | — |
| Enrolling By Invitation | Evaluation of the Effects of High Intensity Laser Therapy and Exercise in Hand Thumb Osteoarthritis NCT07112742 | TC Erciyes University | N/A |
| Not Yet Recruiting | Artificial Intelligence in Trapeziometacarpal Joint Osteoarthritis: Improving Assessment and Clinical Decision NCT07148349 | Schulthess Klinik | — |
| Completed | Extracorporeal Shock Waves Therapy (ESWT) vs Exercise in Thumb Osteoarthritis NCT06056765 | Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari | N/A |
| Recruiting | NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis NCT05992883 | Mayo Clinic | Phase 3 |
| Completed | Pulsed Electromagnetic Field (PEMF) Therapy in Thumb CMC Arthritis NCT05315297 | Stanford University | N/A |
| Unknown | 3D-Printed Hand Orthosis Versus Thermoplastic Orthosis NCT05896410 | Western University, Canada | N/A |
| Unknown | Anatomical Evaluation of the APL Tendons in Thumb CMC Joint and Osteoarthritis NCT05626192 | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | — |
| Completed | Influence of Custom Orthosis Post Carpometacarpal (CMC) Arthroplasty NCT05307510 | University of Toledo | N/A |
| Completed | Assessment and Comparison of Efficacy of Intra-Articular PRP and Corticosteroid in First CMC Joint OA Treatmen NCT06657300 | Antalya Training and Research Hospital | Phase 4 |
| Recruiting | Efficacy of Trapeziectomy Versus Sham Surgery in the Treatment of Osteoarthritis at the Base of the Thumb NCT05127005 | Tampere University Hospital | N/A |
| Withdrawn | Occupational Therapy Pre-operative Education in the Orthopedic Hand Setting NCT05095415 | Methodist University, North Carolina | N/A |
| Completed | Effects of 12-week Digital Treatment in Patients With Hand OA on Pain and Function NCT05499559 | Joint Academy | — |
| Completed | Can Video Assisted Therapy Replace In-Person Occupational Therapy After Hand Surgery: a Noninferiority Study NCT04625244 | Carilion Clinic | N/A |
| Unknown | Trapeziectomy Suspensionplasty Versus Carpometacarpal Joint Replacement in Treatment of Basal Thumb Osteoarthr NCT04588961 | Medical University of Warsaw | N/A |
| Unknown | The Role of the Proprioceptive Training in Functional Recovery of Patient With Thumb Base Osteoarthritis NCT04892589 | Clinica Universitaria Reina Fabiola, Universidad Catolica de Cordoba | — |
| Completed | Effectiveness of Intra-articular Oxygen-ozone Injections and Splinting for the Treatment of Thumb Osteoarthrit NCT07171840 | Humanitas Clinical and Research Center | Phase 3 |
| Recruiting | Variable Immobilization Protocol for Arthroplasty of the Carpometacarpal Joint of the Thumb NCT04828954 | University of Chicago | N/A |
| Completed | Position Sense, Force Control and Pain Intensity in Basal Thumb Osteoarthritis NCT04819139 | University of Malaga | N/A |
| Unknown | Thumb Basal Joint (CMC I) Arthritis - Preoperative Anxiety/Depression, Outcome Instruments, Carpal Cinematics NCT04826380 | Töölö Hospital | N/A |
| Completed | Proprioceptive Thumb Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis NCT04738201 | University of Malaga | N/A |
| Completed | Effectiveness of a Tele-Rehabilitation Evidence-based Tablet App for Rehabilitation in Traumatic Bone and Soft NCT04669704 | University of Seville | N/A |
| Unknown | Autologous Stromal Vascular Fraction in the Treatment of Thumb Basal Joint Osteoarthritis NCT04455763 | Töölö Hospital | N/A |
| Completed | The Use of Intra-articular Corticosteroid Injection to Treat Osteoarthritis of the Carpometacarpal Joint NCT04177433 | University of Alberta | Phase 4 |
| Terminated | Magnesium as an Adjunct for Pain Treatment After Surgery for Thumb Base Arthrosis NCT04613154 | Region Örebro County | N/A |
| Completed | The THumb Osteoarthritis Exercise TriAl NCT05772715 | Erasmus Medical Center | N/A |
| Active Not Recruiting | Trapeziectomy vs. Trapeziometacarpal Limited Excision for Thumb Base Osteoarthritis NCT04210687 | Karolinska Institutet | N/A |
| Completed | A Study on the Effect of Platelet Rich Plasma (PRP) on Osteoarthritis in the Thumb Base NCT04218591 | Karolinska Institutet | N/A |
| Completed | Effectiveness of Proprioceptive Exercises Program in Patients With Carpometacarpal Joint Osteoarthritis NCT04777526 | University of Malaga | N/A |
| Completed | Investigation of Thenar Muscles Morphometric Parameters in Patients With TMC OA NCT04913935 | Hacettepe University | — |
| Unknown | Distraction vs Interposition Arthroplasty for Basilar Thumb Osteoarthritis NCT04155853 | Aristotle University Of Thessaloniki | N/A |
| Unknown | Validity And Reliability of the Turkish Version of the Thumb Disability Examination NCT04627259 | Hacettepe University | — |
| Active Not Recruiting | Study of the Touch® Trapezo-metacarpal Prosthesis NCT03611023 | Groupe Concepteur Touch | — |
| Completed | Thumb Carpometacarpal Joint Denervation Versus Trapeziectomy NCT03558204 | Johns Hopkins University | — |
| Completed | Ligament Reconstruction Weilby vs Simple Trapeziectomy NCT03858946 | University of Southern Denmark | N/A |
| Recruiting | Turmeric for Patients With Basal Joint Arthritis NCT03017118 | Massachusetts General Hospital | N/A |
| Completed | Laser Therapy, Pain and Carpometacarpal Joint Osteoarthritis Treatment NCT03270488 | University of Malaga | N/A |
| Completed | Strengthening of the First Dorsal Interosseous for Thumb Carpometacarpal Osteoarthritis NCT03177577 | Massachusetts General Hospital | N/A |
| Unknown | Postoperative Therapy After Interposition Arthroplasty in CMC1 NCT01679717 | Diakonhjemmet Hospital | N/A |
| Completed | Arthroscopic Resection Arthroplasty of Carpometacarpal and/or Pantrapezial Osteoarthritis NCT02958137 | Orthopaedic Specialist, PC, Davenport, IA | — |