NCT04870879

Colorectal Metastasis and Liver Transplantation With Organs From Deceased Donors

Colorectal Metastasis and Liver Transplantation With Organs From Deceased Donors: an Inductive Padova Center Protocol

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (estimated)
• Sponsor: Azienda Ospedaliera di Padova · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

MELODIC trial is an prospective, multicenter, non-randomized, open-label, parallel trial, aimed at assessing the efficacy (in terms of overall survival: OS) of liver transplantation (LT) in unresecable CRC liver-only metastases, compared with a matched cohort of patients bearing the same tumor characteristics, and treated with chemotherapy. Synthesis of Inclusion parameters: "10;10;10;100"

Conditions

• Colorectal Liver Metastases
• Colorectal Adenocarcinoma
• Unresectable Malignant Neoplasm

Interventions

Type	Name	Description
PROCEDURE	Liver Transplant	Liver Transplant from cadaveric donors
DRUG	Chemotherapy	Chemotherapy

Timeline

• Start date: 2020-10-01
• Primary completion: 2025-10-01
• Completion: 2025-10-01
• First posted: 2021-05-04
• Last updated: 2021-05-04

Locations

1 site across 1 country: Italy