Trials / Completed
CompletedNCT04867304
Determinants of Depression and Its Impact on Quality of Life in Patients With Chronic Pancreatitis
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 625 (actual)
- Sponsor
- Asian Institute of Gastroenterology, India · Academic / Other
- Sex
- All
- Age
- 18 Years – 60 Years
- Healthy volunteers
- Accepted
Summary
Chronic pancreatitis (CP) is associated with recurrent intractable abdominal pain, pancreatic exocrine insufficiency and endocrine dysfunction. Very few studies had evaluated the quality of life in CP, and even a fewer have assessed the mental status in these patients. In the current study, we proposed to evaluate the the relationship between pain, quality of life and depression status in two large independent cohorts of patients with CP. We also proposed to evaluate the brain metabolites in the right and left anterior cingulate cortex, basal ganglia, hippocampus and prefrontal cortex using magnetic resonance spectroscopy. We further proposed to evaluate the pasta metabolites and look for associations with the mental state. Finally, we proposed to evaluate how CP related education of the patients could impact on their mental status and response to interventions on pain.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Patient education about chronic pancreatitis. | Patients in the second cohort were educated about their disease phenotype in a structured and personalised manner that included their disease course, symptoms, imaging, treatment option and possible long-term outcomes and prognosis. This was followed by answering all the queries of the patient and their caregivers. The patients were advised to visit the Pancreas clinic after 3-months for re-evaluation of the clinical, psychological and metabolic parameters. |
Timeline
- Start date
- 2018-02-01
- Primary completion
- 2020-01-31
- Completion
- 2020-01-31
- First posted
- 2021-04-30
- Last updated
- 2021-04-30
Locations
1 site across 1 country: India
Source: ClinicalTrials.gov record NCT04867304. Inclusion in this directory is not an endorsement.