NCT04865471

Resection And Partial Liver Segmental Transplantation With Delayed Total Hepatectomy

Resection And Partial Liver Segmental Transplantation With Delayed Total Hepatectomy as Treatment for Selected Patients With Unresectable Liver Metastases From Colorectal Carcinoma

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (estimated)
• Sponsor: Azienda Ospedaliera di Padova · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

RAPID is an auxiliary liver transplantation where a small liver partial graft (namely left lateral segments from living or cadaveric donors) is implanted orthotopically after a left hepatectomy of the native liver. Subsequently, in order to implement a fast regeneration of the transplanted segments a portal flow diversion is operated in the direction of the future remnant. After obtaining a fast regeneration of the auxiliary future remnant liver the native liver hepatectomy is completed as in a two stage- hepatectomy. Peculiar inclusion criteria will be adopted for patient selection with particular reference to the admission of patients with \<3 lung metastases radically treated before transplantation.

Conditions

• Liver Metastases

Interventions

Type	Name	Description
PROCEDURE	Liver transplantation	Auxiliary liver transplantation and staged hepatectomy

Timeline

• Start date: 2020-10-01
• Primary completion: 2025-10-01
• Completion: 2025-10-01
• First posted: 2021-04-29
• Last updated: 2024-04-23

Locations

1 site across 1 country: Italy