NCT04857541

Breathing Performance of Healthy Young Adult

Investigation of Breathing Performance of Healthy Young Adult

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 65 (actual)
• Sponsor: National Cheng-Kung University Hospital · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Accepted

Summary

The study will recruit subject of healthy adult, COPD-like patient and patient with COPD to investigate the difference of respiratory performance. We will measure the body composition, respiratory muscle force, pulmonary function and performance of voluntary cough. The muscle thickness of abdominal muscle and diaphragm, assessment of diaphragm during different breathing pattern and the muscle activation during voluntary cough will also being determined. We hypothesized that there will be a significantly different between three group on the performance of voluntary cough, and the correlation between each variable will be further investigated.

Detailed description

The specific aims of the study are: 1. difference of respiratory muscle performance between three groups 2. the correlation between respiratory symptom and pulmonary functional test 3. difference of functional respiratory performance (peak cough flow of voluntary cough) between three groups 4. muscle activation of abdominal muscle and diaphragm during performing voluntary force 5. performance of diaphragm under different breathing load

Conditions

• COPD
• COPD-like

Timeline

• Start date: 2021-05-11
• Primary completion: 2021-05-13
• Completion: 2022-04-20
• First posted: 2021-04-23
• Last updated: 2022-06-10

Locations

1 site across 1 country: Taiwan