Trials / Completed
CompletedNCT04856579
Assessment of Seminal Levels of Cystatin C and Endoglin in Infertile Men With Varicocele
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 30 (actual)
- Sponsor
- Benha University · Academic / Other
- Sex
- Male
- Age
- 18 Years – 39 Years
- Healthy volunteers
- Accepted
Summary
Varicocele is a major contributor in male infertility. The improvement of sperm parameters after varicocelectomy supports this contribution. The pathophysiological mechanisms of varicocele-induced male infertility are still under investigation. Cystatin C (Cys C) and endoglin are secreted glycoproteins that recently linked to several cellular changes common in varicocele like apoptosis and autophagy.
Detailed description
Subinguinal varicocelectomy under general anesthesia and complete aseptic condition was done to infertile men with varicocele
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Varicocelectomy | Subinguinal varicocelectomy under general anesthesia and complete aseptic condition |
Timeline
- Start date
- 2019-01-01
- Primary completion
- 2020-12-31
- Completion
- 2020-12-31
- First posted
- 2021-04-23
- Last updated
- 2021-04-23
Locations
2 sites across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04856579. Inclusion in this directory is not an endorsement.