Trials / Unknown
UnknownNCT04834830
Evaluation and Importance of the PD-1/PD-L1 and the IL-10/IL-10R Axis in Malignant and Benign Pleural Effusions - a Pilot Study
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 80 (estimated)
- Sponsor
- University of Vienna · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- —
Summary
The aim of this study is to evaluate the concentrations of interleukin-2, interleukin-10, interferon-gamma, PD1+ lymphocytes, and the interleukin-10 receptor expression in malignant and benign effusions.
Detailed description
In this prospective trial, 80 patients with pleural effusions and indication for thoracocentesis, drainage, indwelling pleural catheter (IPC) management and/or video-assisted thoracoscopic surgery are enrolled. The pleural effusion will be examined for different cytokines, cytokine-receptors, PD1-lymphocytes and CD4+/CD25+/Foxp3+ regulatory T cell.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIAGNOSTIC_TEST | Pleural effusion will be examined for various cytokines and PD1-lymphocytes. | Examination of pleural effusion |
Timeline
- Start date
- 2021-04-01
- Primary completion
- 2022-04-01
- Completion
- 2022-04-01
- First posted
- 2021-04-08
- Last updated
- 2021-04-08
Locations
1 site across 1 country: Austria
Source: ClinicalTrials.gov record NCT04834830. Inclusion in this directory is not an endorsement.