Trials / Completed
CompletedNCT04830995
Insulin Sensitivity Response to High-Intensity Training in Insulin Resistance During Pregnancy
Impact of High-Intensity Interval Training on Insulin Resistance During Pregnancy: A Randomized Control Trial.
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- Cairo University · Academic / Other
- Sex
- Female
- Age
- 25 Years – 35 Years
- Healthy volunteers
- Not accepted
Summary
Insulin Resistance is one of the common complications that occur during pregnancy. Early intervention is essential to prevent the development of the diseaseThere is evidence that physical inactivity increases the risk of a lot of adverse health problems, including coronary heart disease, type 2 diabetes, breast and colon cancers. It also shortens life expectancy. Pregnancy is a period in the life of women that is often associated with decreased daily physical activity and decreased participation in sports and exercise . In the first few weeks of pregnancy, maternal carbohydrate metabolism is affected by a rise in maternal levels of estrogen and progesterone that stimulates pancreatic β-cell hyperplasia and insulin secretion. As pregnancy progress, pancreatic islet cell hypertrophy continues and there is an increased insulin response to glucose or meal stimulation.
Detailed description
This study was carried out upon twenty multigravida pregnant female between 5-6 months gestation with IR calculated by HOMA test (fasting blood glucose× fasting insulin) ÷ 22.5. Fasting blood glucose was assessed by the method approved by (7, 13) .The test materials for this method were supplied as kits by "Diamond Diagnostics," while Insulin concentrations were stated in formerly frozen and defrosted serum samples by enzyme immunoassay using the human Insulin ELISA kits.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | moderate restricted diet (1800-2000 kcal/day) for four weeks | high intensity interval training 3 sessions for four weeks |
Timeline
- Start date
- 2020-03-24
- Primary completion
- 2020-10-30
- Completion
- 2020-11-01
- First posted
- 2021-04-05
- Last updated
- 2023-01-19
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT04830995. Inclusion in this directory is not an endorsement.