Clinical Trials Directory

Trials / Terminated

TerminatedNCT04790916

Effect of RO7049665 on the Time to Relapse Following Steroid Tapering in Participants With Autoimmune Hepatitis (AIH)

A Double-Blind, Randomized, Parallel-Group, Phase 2 Study to Investigate the Effect of RO7049665 on the Time to Relapse Following Steroid Tapering in Patients With Autoimmune Hepatitis

Status
Terminated
Phase
Phase 2
Study type
Interventional
Enrollment
2 (actual)
Sponsor
Hoffmann-La Roche · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

The primary objective of the study is to evaluate the effect of RO7049665 on time to relapse following forced corticosteroid (CCS) tapering as measured by the hazard ratio between RO7049665 7.5 milligrams (mg) and placebo arm.

Conditions

Interventions

TypeNameDescription
DRUGRO7049665RO7049665, subcutaneous injection, Q2W.
OTHERPlaceboRO7049665-matching placebo, subcutaneous injection, Q2W.

Timeline

Start date
2021-04-19
Primary completion
2021-11-18
Completion
2021-11-18
First posted
2021-03-10
Last updated
2023-09-18
Results posted
2023-09-18

Locations

14 sites across 8 countries: Australia, Canada, Germany, Italy, Netherlands, Portugal, South Korea, United Kingdom

Source: ClinicalTrials.gov record NCT04790916. Inclusion in this directory is not an endorsement.

Effect of RO7049665 on the Time to Relapse Following Steroid Tapering in Participants With Autoimmune Hepatitis (AIH) (NCT04790916) · Clinical Trials Directory