Clinical Trials Directory

Trials / Completed

CompletedNCT04779125

APEMESH II - Perineal Reconstruction

Apemesh II - Perineal Reconstruction With Mesh Enhanced Gluteus Plasty

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
30 (actual)
Sponsor
University of Oulu · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The objective of this pilot study is to assess the safety, functional outcome, feasibility and the potential benefits of synthetic mesh strip and gluteus flap reconstruction in perineum in case-control setting.

Detailed description

Several studies have reported over 30% morbidity with perineal wound healing after abdominoperineal resection. Preoperative radiotherapy seems to be a strong predictor for perineal complications. Musculocutaneus flaps and use of biological mesh seem to minimize perineal morbidity.

Conditions

Interventions

TypeNameDescription
PROCEDUREGluteus plasty enhanced with Progrip self gripping meshIntervention group will be compared to historical patients in a case-control setting. Intervention group will have a mesh enhanced gluteus plasty made to reconstruct perineum after abdominoperineal resection.

Timeline

Start date
2021-03-19
Primary completion
2022-03-01
Completion
2022-03-01
First posted
2021-03-03
Last updated
2024-02-01

Locations

1 site across 1 country: Finland

Source: ClinicalTrials.gov record NCT04779125. Inclusion in this directory is not an endorsement.