Trials / Completed
CompletedNCT04776837
Predicting Disease Progression and/or Recurrence in Cancer
Tumor Markers, Liquid Biopsies, and Patient Reported Outcomes in Metastatic Colorectal, Pancreas, Biliary, and Esophagogastric Cancers
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 200 (actual)
- Sponsor
- Massachusetts General Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This is a prospective study addressing the challenge of predicting disease progression and/or recurrence in patients diagnosed with metastatic colorectal, pancreatobiliary, or esophagogastric cancer that are receiving anti-cancer therapy.
Detailed description
This research study is evaluating how patient-reported outcomes (e.g. symptoms, quality of life) and biomarkers compare to standard of care clinical assessments such as imaging and tumor markers in predicting the clinical outcomes (e.g. disease progression and survival) in patient populations with colorectal, pancreatobiliary, or esophagogastric cancer that are receiving anti-cancer therapy Massachusetts General Hospital Cancer Center * Patient reported outcomes will be collected through a series of self-administered questionnaires and blood draws will be used to obtain bio and tumor marker information. * Information will also be collected from the participants electronic medical record. * Tissue may be obtained for next-generation sequencing. * The study will conclude after participants are no longer receiving anti-cancer therapies. * It is expected that about 200 people will take part in this research study
Conditions
- Patient Reported Outcome Measures
- Colorectal Cancer
- Pancreatic Cancer
- Biliary Tract Cancer
- Esophageal Cancer
- Metastatic Cancer
- Disease Progression
- Survival Analysis
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Observational Cohort | Patients will be followed by collecting clinical data, biospecimens, and quality of life assessment |
Timeline
- Start date
- 2019-05-15
- Primary completion
- 2021-11-19
- Completion
- 2021-11-19
- First posted
- 2021-03-02
- Last updated
- 2022-08-04
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT04776837. Inclusion in this directory is not an endorsement.