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TerminatedNCT04776746

Open-Label Extension Study of Trofinetide for Rett Syndrome

An Open-Label Extension Study of Continuing Treatment With Trofinetide for Rett Syndrome

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
77 (actual)
Sponsor
ACADIA Pharmaceuticals Inc. · Industry
Sex
Female
Age
5 Years – 21 Years
Healthy volunteers
Not accepted

Summary

To investigate the safety and tolerability of continued long-term treatment with oral trofinetide in girls and women with Rett syndrome

Conditions

Interventions

TypeNameDescription
DRUGtrofinetideStudy drug is administered twice a day for up to approximately 32 months. Doses may be taken orally or administered by gastrostomy (G) tube. The subject's assigned dose for this study will be the final dose from the antecedent study (ACP-2566-004).

Timeline

Start date
2020-11-08
Primary completion
2023-06-30
Completion
2023-06-30
First posted
2021-03-02
Last updated
2024-09-27
Results posted
2024-09-27

Locations

21 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04776746. Inclusion in this directory is not an endorsement.

Open-Label Extension Study of Trofinetide for Rett Syndrome (NCT04776746) · Clinical Trials Directory