Clinical Trials Directory

Trials / Completed

CompletedNCT04771845

Transcranial Magnetic Stimulation in Mild Cognitive Impairment and Alzheimer Disease

Transcranial Magnetic Stimulation (TMS) in Patients With Mild Cognitive Impairment (MCI) and Alzheimer Disease (AD): A Twelve-year Retrospective Observational Study

Status
Completed
Phase
Study type
Observational
Enrollment
73 (actual)
Sponsor
The New York Memory Services · Academic / Other
Sex
All
Age
Healthy volunteers
Not accepted

Summary

The investigators reviewed 12 years of clinical use in an outpatient neurology setting of transcranial magnetic stimulation (TMS) in patients with Alzheimer's disease (AD) and mild cognitive impairment (MCI) to evaluate safety and efficacy of TMS.

Detailed description

The investigators compiled demographic, clinical, and neurocognitive data on all patients who had received TMS for any reason in the clinic over a 12-year period. Of 236 patients receiving TMS, 59 patients with AD and 14 with MCI satisfied study criteria and were compared to controls from the National Alzheimer's Coordinating Center (NACC). Neurocognitive outcomes were compared between magnetic resonance imaging (MRI) and electroencephalogram (EEG)-grid guided TMS in patients. Tolerability data was reviewed for all patients.

Conditions

Interventions

TypeNameDescription
DEVICETranscranial Magnetic StimulationMagnetic stimulation to alter neural activity

Timeline

Start date
2008-05-01
Primary completion
2020-05-30
Completion
2020-05-30
First posted
2021-02-25
Last updated
2021-02-25

Regulatory

Source: ClinicalTrials.gov record NCT04771845. Inclusion in this directory is not an endorsement.