NCT04766528

Effect of Diet on the Microbiota / Endoccanabinoidome Axis in Response to Physical Activity

Effect of Dietary Composition on the Gut Microbiota / Endocannabinoidome Axis in Response to Maximal Aerobic Exercise

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 11 (actual)
• Sponsor: Laval University · Academic / Other
• Sex: Female
• Age: 20 Years – 30 Years
• Healthy volunteers: Accepted

Summary

Both the endocannabinoid system and the microbiome are highly conditioned by nutrition and physical activity, and have an interdependent, bidirectional relationship. We suggest studying the interleaving between the endocannabinoidome-microbiome axis and host metabolism under the combined effect of a diet and physical activity. More specificly, we will study the link between the impact of the diet on the intestinal microbiome and the endocannabinoid reaction after intense exercise.

Detailed description

Aims of the study are to compare the impacts of two short 7-day contrasted nutritional interventions (the Mediterranean diet (MED) and the Canadian diet (CAN)) on blood metabolites (endocannabinoids) after a maximal aerobic test. A 3 weeks washout between the two diets is planned. Gut microbiome at each test will also be evaluated.

Conditions

• Diet Habit
• Microbial Colonization
• Activity, Motor

Interventions

Type	Name	Description
OTHER	3 maximal aerobic tests	Maximal aerobic tests will be performed before diet intervention, after the first diet and after the second diet

Timeline

• Start date: 2019-09-06
• Primary completion: 2019-11-14
• Completion: 2019-11-14
• First posted: 2021-02-23
• Last updated: 2021-02-23

Locations

1 site across 1 country: Canada