NCT04709185

AVS After 1mg DST to Determine Subtype in PA

Adrenal Venous Sampling Under 1 mg Overnight Dexamethasone Suppression Test to Determine Subtype in Primary Aldosteronism，a Single Center, Randomized, Double Blended, Placebo Controlled Clinical Trail

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 110 (actual)
• Sponsor: Shanghai Zhongshan Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To compare the effect of different procedures of AVS(after 1mg DST or not) in determining the subtypes and long-term outcomes of PA

Detailed description

All paticipants will be randomly divided into 1mg DST group(Intervention group,n=43) and placebo group(Control group,n=43) and to determining the subtypes and to compare the long-term outcomes of patients with PA.

Conditions

• Primary Aldosteronism

Interventions

Type	Name	Description
DRUG	Dexamethasone 1 MG Oral Tablet	oral 1 mg dexamethasone at 23:00-24:00 the night before AVS
DRUG	Placebo	oral placebo at 23:00-24:00 the night before AVS

Timeline

• Start date: 2021-01-08
• Primary completion: 2022-10-30
• Completion: 2022-12-30
• First posted: 2021-01-14
• Last updated: 2023-06-01

Locations

1 site across 1 country: China