NCT04687475

Implementation of a Clinical Tool to Improve Waitlist Mortality in Patients With Cystic Fibrosis

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: The Cleveland Clinic · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Implementation of a Clinical Tool to Improve Waitlist Mortality in Patients With Cystic Fibrosis

Detailed description

The aim of this project is to implement a clinical tool utilizing predictors of mortality for patients with Cystic Fibrosis (CF) on the waiting list to identify candidates that should present for urgent medical care and, if appropriate, will prompt clinicians to update a candidate's lung allocation score (LAS), the score used to prioritize lung transplant candidates for transplant by medical urgency, and avoid undetected decline. The clinical tool consists of home spirometry measures and patient reported outcomes that is completed weekly on a mobile application device used clinically to track spirometry.

Conditions

• Cystic Fibrosis
• Lung Transplant; Complications

Interventions

Type	Name	Description
OTHER	Clinical Tool (Mobile Spirometry and Survey)	The clinical tool is a combination of home spirometry measurements and a patient survey measuring patient reported outcomes including the Cystic Fibrosis Respiratory Symptom Diary (CFRSD) and Chronic Respiratory Infection Symptom Score (CRISS©), with permission from the Seattle Quality of Life Group.

Timeline

• Start date: 2020-04-20
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2020-12-29
• Last updated: 2025-07-10

Locations

1 site across 1 country: United States