NCT04644692

Effort-Lung Ultra Sound

Positive Diagnosis of Heart Failure With Preserved LVEF by Exercise Pulmonary Ultrasound.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 56 (actual)
• Sponsor: Central Hospital, Nancy, France · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Accepted

Summary

The E-LUS study is a prospective, non randomised, monocenter case-control study. The main objective is to evaluate the association of exercise lung ultrasound data acquired during a stress test on a bicycle ergometer with the diagnosis of heart failure with preserved ejection fraction (HFpEF).

Detailed description

Secondary objectives: 1. To assess the diagnostic performance of exercise lung ultrasound for the diagnosis of HFpEF. 2. To identify the value of the B-lines score on exercise maximizing the sensitivity and specificity for the diagnosis of HFpEF. 3. To evaluate the relationship of the delta of B-lines scores between rest and exercise with the diagnosis of HFpEF. 4. To assess the diagnostic performance of the delta of B-lines between rest and exercise for the diagnosis of HFpEF. 5. To identify the score of the delta of B-lines value between rest and exercise maximizing sensitivity and specificity for the diagnosis of HFpEF. 6. To evaluate the relationship between the resting value of the B-lines scores with the diagnosis of HFpEF. 7. To assess the diagnostic performance of the resting lung ultrasound for the diagnosis of HFpEF. 8. To identify the value of the B-lines score at rest maximizing the sensitivity and specificity for the diagnosis of HFpEF. 9. To evaluate the correlation between the B-line score measured at rest and exercise and the dyspnoea score measured at rest, during exercise, and during the recovery phase. 10. To assess the correlation of the delta of B-lines scores between rest and exercise and the dyspnoea score measured at rest, during exercise and during the recovery phase.

Conditions

• Heart Failure With Preserved Ejection Fraction

Interventions

Type	Name	Description
OTHER	Lung ultrasound	A lung ultrasound before and at the end of the stress test.

Timeline

• Start date: 2021-01-18
• Primary completion: 2021-12-21
• Completion: 2022-05-17
• First posted: 2020-11-25
• Last updated: 2023-03-13

Locations

1 site across 1 country: France