NCT04640285

Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With Use of RELX ENDS Products by Smokers

A Randomized, Open-Label, Single-Center, Cross-Over Study of Adult Smokers to Assess Nicotine Uptake, Measures of Abuse Liability, and Puffing Topography With RELX Infinity Electronic Nicotine Delivery Systems (ENDS)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Cheerain HK Limited · Industry
• Sex: All
• Age: 22 Years – 59 Years
• Healthy volunteers: Accepted

Summary

This study is being conducted to evaluate nicotine uptake and exposure, the abuse liability, and puffing topography associated with the use of an electronic nicotine delivery system ENDS with tobacco- and menthol-flavored e-liquids in current smokers.

Conditions

• Electronic Cigarette Use

Interventions

Type	Name	Description
OTHER	RELX ENDS Tobacco Flavor	Ad libitum use of RELX ENDS tobacco flavor product during 8-hour and 5-minute use sessions
OTHER	RELX ENDS Menthol Flavor	Ad libitum use of RELX ENDS Menthol flavor product during 8-hour and 5-minute use sessions
OTHER	Usual Brand Cigarette	Ad libitum use of subjects usual brand product during 8-hour and single cigarette use sessions
OTHER	Nicorette White Ice Mint nicotine polacrilex gum	Ad libitum use of Nicorette White Ice Mint nicotine polacrilex gum product during 8-hour and 30-minute use sessions

Timeline

• Start date: 2020-11-03
• Primary completion: 2021-03-12
• Completion: 2021-03-19
• First posted: 2020-11-23
• Last updated: 2021-03-24

Locations

1 site across 1 country: United States