NCT04622397

Local Subfascial and Intramuscular Tranexamic Acid Administration in Pediatric Patient Undergoing Scoliosis Surgery, Double Blind Randomized Control Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 2 Years – 12 Years
• Healthy volunteers: Not accepted

Summary

We hypothesized that local administration of tranexamic acid will minimize blood loss and blood product administration in pediatric patient undergoing scoliosis surgery

Detailed description

Spine surgery in paediatrics is frequently associated with substantial blood loss. Blood product adminestration in children has many complications that are not fully known. There are many modalities currently available to reduce blood loss in pediatric patients. Tranexamic acid is tissue plasminogen activator inhibitor that reduce perioperative blood loss. To date, no studies have investigated effect of local administration of tranexamic acid in pediatric population undergoing scoliosis surgery.

Conditions

• Blood Loss, Surgical
• Scoliosis

Interventions

Type	Name	Description
DRUG	Tranexamic acid injection	Local subfascial and intramuscular infiltration will be performed by surgeon at levels of fixation prior to skine incision
DRUG	Saline	Local subfascial and intramuscular infiltration will be performed by surgeon at levels of fixation prior to skine incision

Timeline

• Start date: 2021-01-10
• Primary completion: 2021-11-29
• Completion: 2021-12-29
• First posted: 2020-11-10
• Last updated: 2020-11-10