Clinical Trials Directory

Trials / Completed

CompletedNCT04617028

Jaktinib Versus Hydroxycarbamide in Subjects With Intermediate-2 or High-risk Myelofibrosis

A Randomized, Double-blind, Double-simulated, Parallel-controlled, Multicenter Phase III Study Evaluating the Efficacy and Safety of Jaktinib Versus Hydroxycarbamide in Patients With Intermediate-2 or High-risk Myelofibrosis

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
105 (actual)
Sponsor
Suzhou Zelgen Biopharmaceuticals Co.,Ltd · Industry
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

This study is to determine the efficacy of Jaktinib versus Hydroxycarbamid in participants with Intermediate-2 or High-risk myelofibrosis

Conditions

Interventions

TypeNameDescription
DRUGJaktinibJaktinib Hydrochloride Tablets administered orally twice daily
DRUGPlacebo to match HydroxycarbamidePlacebo to match Hydroxycarbamide Tablets administered orally twice daily
DRUGHydroxycarbamide TabletsHydroxycarbamide Tablets administered orally twice daily
DRUGPlacebo to match JaktinibPlacebo to match Jaktinib Tablets administered orally twice daily

Timeline

Start date
2021-02-05
Primary completion
2023-10-18
Completion
2023-10-18
First posted
2020-11-05
Last updated
2023-11-13

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04617028. Inclusion in this directory is not an endorsement.