| Not Yet Recruiting | Study of ZG006 in Combination With PD-1/PD-L1 Immune Checkpoint Inhibitors as First-Line Standard Therapy in P Small Cell Lung Cancer | Phase 1 | 2026-03-01 |
| Recruiting | Study Comparing ZG006 With Investigator-Selected Chemotherapy in Participants With Relapsed Small Cell Lung Ca Small-cell Lung Cancer | Phase 3 | 2025-12-12 |
| Not Yet Recruiting | Study of ZGGS34 in Participants With Advanced Solid Tumors Solid Tumor | Phase 1 / Phase 2 | 2025-12-01 |
| Recruiting | ZG006 and ZG005 in Participants With Small Cell Lung Cancer or Neuroendocrine Carcinoma Small Cell Lung Cancer, Neuroendocrine Carcinoma | Phase 1 / Phase 2 | 2025-09-23 |
| Recruiting | Study of ZG005 in Combination With Gecacitinib in Participants With Advanced Cervical Cancer Cervical Cancer | Phase 1 / Phase 2 | 2025-09-23 |
| Not Yet Recruiting | Study of ZG005 in Combination With Gecacitinib and Chemotherapy for Participants With Advanced Solid Tumors Advanced Solid Tumor | Phase 1 / Phase 2 | 2025-09-01 |
| Not Yet Recruiting | Study of ZG005 in Combination With Platinum-Based Chemotherapy in Participants With Advanced Biliary Tract Car Biliary Tract Carcinoma | Phase 2 | 2025-09-01 |
| Not Yet Recruiting | Study of ZG006 in Participants With Neuroendocrine Prostate Cancer Neuroendocrine Prostate Cancer | Phase 2 | 2025-08-01 |
| Recruiting | Study of ZG005 in Patients With Advanced Solid Tumors Advanced Solid Tumor | Phase 2 | 2025-06-13 |
| Recruiting | Study of ZG005 Combined With Gecacitinib in Patients With Advanced Non-Small Cell Lung Cancer Non-small Cell Lung Cancer | Phase 1 / Phase 2 | 2025-05-23 |
| Recruiting | Study of ZGGS18 in Combination With ZG005 in Patients With Advanced Solid Tumors Advanced Solid Tumor | Phase 1 / Phase 2 | 2025-05-20 |
| Recruiting | Study of ZG005 in Combination With Gecacitinib in Patients With Relapsed or Refractory Lymphoma Lymphoma | Phase 1 / Phase 2 | 2025-05-16 |
| Recruiting | A Phase 1 Dose Escalation Study of ZG006 in Patients With Small Cell Lung Cancer Small Cell Lung Cancer | Phase 1 | 2025-03-31 |
| Unknown | A Study of Jaktinib for the Treatment of Steroid-Refractory Acute Graft-Versus-Host Disease. Acute Graft-Versus-Host Disease | Phase 2 | 2024-12-01 |
| Recruiting | Study of ZG005 Combined With Bevacizumab Versus Sintilimab Combined With Bevacizumab in Advanced Hepatocellula Hepatocellular Carcinoma | Phase 2 | 2024-10-24 |
| Recruiting | Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinom Small Cell Lung Cancer, Neuroendocrine Cancer | Phase 1 / Phase 2 | 2024-09-02 |
| Recruiting | Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinom Neuroendocrine Carcinoma | Phase 1 / Phase 2 | 2024-08-29 |
| Unknown | A Safety and Tolerability Study of Jaktinib Myelofibrosis | Phase 1 | 2024-07-01 |
| Recruiting | Study of ZG005 in Combination With Etoposide and Cisplatin in Participants With Advanced Neuroendocrine Carcin Neuroendocrine Carcinoma | Phase 1 / Phase 2 | 2024-05-30 |
| Recruiting | A Study of ZG005 Combined With Donafenib in Patients With Advanced Solid Tumor Solid Tumor | Phase 1 / Phase 2 | 2024-05-10 |
| Unknown | An Efficacy and Safety Study of Jaktinib Hydrochloride Tablets in the Treatment of Severe Novel Coronavirus Pn Novel COVID-19-Infected Pneumonia | Phase 2 | 2024-04-01 |
| Unknown | A Study of Jaktinib Hydrochloride Tablets in the Treatment of Severe Novel Coronavirus Pneumonia Novel COVID-19-Infected Pneumonia | Phase 2 | 2024-04-01 |
| Recruiting | Study of ZG005 in Combination With Paclitaxel＋Platinum-based ± Bevacizumab in Patients With Advanced Cervical Cervical Carcinoma | Phase 1 / Phase 2 | 2024-03-27 |
| Completed | A Study to Evaluate the Effect of Jaktinib on QT/QTc Interval in Healthy Participants Healthy Participants | Phase 1 | 2024-03-19 |
| Completed | Comparative Study on Pharmacokinetics of Two Formulations of Jaktinib in Healthy Adults Under Fasting Conditio Myelofibrosis | Phase 1 | 2023-11-29 |
| Unknown | Extension Study to Evaluate Safety and Efficacy of Jaktinib in Patients With Active Ankylosing Spondylitis(AS) Ankylosing Spondylitis | Phase 3 | 2023-11-10 |
| Recruiting | Study of ZG006 in Participants With Small Cell Lung Cancer or Neuroendocrine Carcinoma Small Cell Lung Cancer, Neuroendocrine Carcinoma | Phase 1 / Phase 2 | 2023-10-27 |
| Unknown | A Study of ZG2001 in Participants With KRAS Mutated Advanced Solid Tumours Solid Tumor, KRAS Mutation-Related Tumors | Phase 1 / Phase 2 | 2023-08-10 |
| Recruiting | Study of ZG0895.HCl in Patients With Advanced Solid Tumors Advanced Solid Tumor | Phase 1 | 2023-08-08 |
| Active Not Recruiting | Efficacy and Safety Study of Jaktinib in Subjects With Active Ankylosing Spondylitis(AS) Ankylosing Spondylitis | Phase 3 | 2023-07-20 |
| Completed | Study of ZGGS15 in Patients With Advanced Solid Tumors Advanced Solid Tumors | Phase 1 | 2023-07-19 |
| Unknown | A Phase III Extended Clinical Trial of Jaktinib Hydrochloride Tablets in the Treatment of Moderate and Severe Atopic Dermatitis | Phase 3 | 2023-01-11 |
| Recruiting | Study of ZGGS18 in Patients With Advanced Solid Tumors Advanced Solid Tumor | Phase 1 / Phase 2 | 2022-11-15 |
| Withdrawn | Efficacy and Safety of Jaktinib in Participants With Severe Novel Coronavirus Pneumonia(COVID-19) COVID-19, Pneumonia | Phase 2 | 2022-09-01 |
| Active Not Recruiting | A Phase III Study of Jaktinib in Adults With Moderate and Severe Atopic Dermatitis Atopic Dermatitis | Phase 3 | 2022-07-14 |
| Recruiting | A Study of ZG005 in Patients With Advanced Solid Tumors Solid Tumors | Phase 1 / Phase 2 | 2022-06-17 |
| Unknown | A Study of ZG19018 in Patients With KRAS G12C Mutant Advanced Solid Tumors. KRAS G12C Mutant Advanced Solid Tumors | Phase 1 / Phase 2 | 2022-05-26 |
| Completed | Extension Study to Evaluate Safety and Efficacy of Jaktinib in Adults With Alopecia Areata Alopecia Areata | Phase 3 | 2022-03-25 |
| Completed | ADME Study of [14C]-Jaktinib in Healthy Male Subjects Healthy Adult Male Volunteers | Phase 1 | 2022-01-04 |
| Completed | A Study to Evaluate the Effect of Itraconazole and Rifampicin on the Pharmacokinetics of Jaktinib in Healthy V Healthy Volunteers | Phase 1 | 2021-10-27 |
| Unknown | Efficacy and Safety Study of rhTSH for Adjuvant Radioiodine Ablation Therapy in Patients With Differentiated T Differentiated Thyroid Cancer | Phase 3 | 2021-10-06 |
| Terminated | Jaktinib and Azacitidine In Treating Patients With MDS With MF or MDS/MPN With MF. Myelodysplastic Syndromes, Myeloproliferative Neoplasms, Myelofibrosis | Phase 1 / Phase 2 | 2021-09-30 |
| Completed | Comparison of the Efficacy and Safety of rhTSH as An Adjunctive Diagnostic Tool in Differentiated Thyroid Canc Differentiated Thyroid Cancer | Phase 3 | 2021-09-10 |
| Completed | Study to Evaluate the Safety and Efficacy of Jaktinib in Adults With Alopecia Areata Alopecia Areata | Phase 3 | 2021-09-04 |
| Completed | Pharmacokinetics Of Jaktinib In Subjects With Hepatic Impairment And Normal Hepatic Function Hepatic Insufficiency, Healthy Subjects | Phase 1 | 2021-08-27 |
| Completed | Study of Jaktinib In Patients With Myelofibrosis Who Were Relapsed or Refractory of Ruxolitinib Treatment. Myelofibrosis | Phase 2 | 2021-07-28 |
| Completed | A Phase 2 Study of Jaktinib in Participants With Moderate to Severe Psoriasis Moderate-to-Severe Plaque Psoriasis | Phase 2 | 2021-03-11 |
| Completed | Jaktinib Versus Hydroxycarbamide in Subjects With Intermediate-2 or High-risk Myelofibrosis Myelofibrosis | Phase 3 | 2021-02-05 |
| Unknown | A Phase 1/2 Study of Donafenib in Combination With KN046 in Advanced Gastrointestinal Tumors Advanced Gastrointestinal Tumors | Phase 1 / Phase 2 | 2021-01-19 |
| Unknown | Donafenib and Toripalimab Combined With TACE in Patients With Unresectable Hepatocellular Carcinoma Unresectable Hepatocellular Carcinoma | Phase 1 | 2021-01-08 |
| Completed | Clinical Study of Jaktinib in the Treatment of Patients With Moderate and Severe Atopic Dermatitis Atopic Dermatitis | Phase 2 | 2020-12-02 |
| Completed | Jaktinib Hydrochloride Tablets In The Treatment of Active Ankylosing Spondylitis Ankylosing Spondylitis | Phase 2 | 2020-12-01 |
| Unknown | The Safety and Effectiveness of rhTSH in Radioiodine Treatment for Patients With Differentiated Thyroid Cancer Differentiated Thyroid Cancer | Phase 2 | 2020-11-23 |
| Unknown | Toripalimab Combined With Donafenib in the Treatment of Advanced Hepatocellular Carcinoma Advanced Hepatocellular Carcinoma | Phase 1 / Phase 2 | 2020-10-15 |
| Unknown | A Study of CS1001 in Combination With Donafenib in Subjects With Advanced Solid Tumors Advanced Solid Tumor | Phase 1 | 2020-10-15 |
| Completed | Jaktinib Hydrochloride Cream For Atopic Dermatitis Atopic Dermatitis | Phase 1 / Phase 2 | 2020-10-14 |
| Completed | Study of Jaktinib Hydrochloride Tablets in Participants With Idiopathic Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis | Phase 2 | 2020-09-08 |
| Unknown | A Study With Jaktinib Hydrochloride Cream Applied Topically to Subjects With Alopecia Areata Alopecia Areata(AA) | Phase 1 / Phase 2 | 2020-08-12 |
| Terminated | Alkotinib Capsule in Patients With ALK-positive Non-small Cell Lung Cancer Previously Treated With Crizotinib ALK-positive Non-small Cell Lung Cancer | Phase 2 | 2020-01-21 |
| Completed | Jaktinib for the Treatment of Ruxolitinib Intolerance of Myelofibrosis Primary Myelofibrosis (PMF), Post-polycythemia Vera Myelofibrosis(Post-PV MF), Post-essential Thrombocythemia Myelofibrosis(Post-ET MF) | Phase 2 | 2020-01-07 |
| Completed | To Evaluate the Effect of Food on the Pharmacokinetic Characteristics of Alkotinib Capsules in Healthy Subject NSCLC | Phase 1 | 2019-11-20 |
| Completed | Study to Evaluate the Safety and Efficacy ofJaktinib Hydrochloride Tablets in Severe Alopecia Areata Alopecia Areata | Phase 2 | 2019-11-18 |
| Completed | Safety and Efficacy of Topical Recombinant Human Thrombin(rhThrombin) for Surgical Hemostasis Surgical Hemostasis | Phase 3 | 2019-11-11 |
| Completed | Clinical Trial of Dose-tolerance, Pharmacokinetics and Iodine Uptake For rhTSH In Post-thyroidectomized Patien Differentiated Thyroid Cancer | Phase 1 / Phase 2 | 2019-06-10 |
| Completed | Jaktinib Hydrochloride Tablets in Intermediate-risk and High-risk Myelofibrosis. Myelofibrosis | Phase 2 | 2019-01-08 |
| Terminated | Combination of Donafenib and Cytarabine/Daunorubicin in Relapsed AML Acute Myeloid Leukemia (AML) | Phase 1 | 2018-11-06 |
| Completed | Study of Alkotinib in Patients With Advanced Non Small Cell Lung Cancer Non-small Cell Lung Cancer | Phase 1 | 2018-10-18 |
| Completed | The Mass Balance and Biotransformation of [14C]Donafenib in Healthy Adult Man Healthy Male Adult | Phase 1 | 2018-10-09 |
| Terminated | A Phase 3 Study of Donafenib in Patients With Radioiodine-refractory Differentiated Thyroid Cancer Differentiated Thyroid Cancer | Phase 3 | 2018-08-29 |
| Completed | Topical rhThrombin as an Adjunct to Hemostasis During Segmental Hepatectomy Hepatectomy | Phase 1 / Phase 2 | 2017-11-29 |
| Completed | The Tolerance, Pharmacokinetics of Jaktinib in Healthy Volunteers Healthy Volunteers | Phase 1 | 2017-09-28 |
| Terminated | Donafenib Monotherapy for Previously Treated Metastatic Nasopharyngeal Carcinoma Nasopharyngeal Carcinoma | Phase 1 / Phase 2 | 2017-02-08 |
| Completed | Donafenib for Previously Treated Metastatic Colorectal Cancer Metastatic Colorectal Cancer | Phase 3 | 2016-12-28 |
| Completed | Phase 2 Trial of Donafenib in 131I-Refractory Differentiated Thyroid Cancer Differentiated Thyroid Cancer | Phase 2 | 2016-09-01 |
| Terminated | Donafenib Monotherapy for Previously Treated Metastatic Gastric Cancer Gastric Cancer | Phase 1 / Phase 2 | 2016-05-16 |
| Completed | Efficacy and Safety of Donafenib in Patients With Advanced Hepatocellular Carcinoma HCC | Phase 2 / Phase 3 | 2016-03-01 |
| Terminated | A Study of Donafenib Monotherapy in Advanced Oesophageal Cancer Oesophageal Cancer | Phase 1 / Phase 2 | 2015-07-21 |
| Completed | Safety and Efficacy of Donafenib in Patients With Advanced Hepatocellular Carcinoma HCC | Phase 1 / Phase 2 | 2014-04-01 |
| Completed | Donafenib Monotherapy for Previously Treated Metastatic Colorectal Cancer Metastatic Colorectal Cancer | Phase 1 / Phase 2 | 2014-03-01 |