NCT04608279

Urinary Creatinin/Protein Ratio in Preterms

Evolution of the Proteinuria / Creatininuria Ratio in the First Month of Life in the Preterm Infant

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 124 (actual)
• Sponsor: Centre Hospitalier Universitaire de la Réunion · Academic / Other
• Sex: All
• Age: 1 Day – 2 Days
• Healthy volunteers: Not accepted

Summary

From the first days of life, the newborn presents a "physiological" proteinuria explained by the coexistence of a glomerular and tubular immaturity, all the more marked as the gestational age (GA) is weak. In the child term, proteinuria decreases the first month and its persistence is the marker of kidney damage. The persistence of proteinuria in preterm infants is also considered a marker of renal impairment; however, neither the "physiological" values nor the pattern of urinary excretion of proteins in the first month of life are known. The proteinuria / creatininuria ratio is a validated indicator of proteinuria, as it is correlated with 24-hour urine proteinuria.

Conditions

• Preterm Infant
• Renal Failure

Timeline

• Start date: 2017-01-01
• Primary completion: 2020-01-01
• Completion: 2020-01-01
• First posted: 2020-10-29
• Last updated: 2020-10-29

Locations

1 site across 1 country: France