NCT04600544

Russian Disc Degeneration Study

Disease-oriented Russian Disc Degeneration Study (RuDDS) Biobank Facilitating Functional Omics Studies of Lumbar Disc Degeneration

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,070 (actual)
• Sponsor: Novosibirsk State University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: —

Summary

The main aim of this study is to establish disease-oriented biobank to facilitate research in biology of the lumbar disc degeneration. Diverse biological samples (whole blood, plasma, disc tissue) along with MRI imaging, clinical, socio-demographic and various omics data (e.g. genomic and transcriptomic) will be available for researchers and clinicians for a variety of further multi-omics studies. It will lay the groundwork for the development of early diagnostics of DDD and its personalized treatment. The study is planned to enroll up to 1,100 patients with different grades of lumbar disc degeneration. It is planned to recruit patients within 36 months.

Conditions

• Intervertebral Disc Degeneration
• Genetic Predisposition to Disease

Interventions

Type	Name	Description
OTHER	Non-interventional	Translational, observational study

Timeline

• Start date: 2020-10-16
• Primary completion: 2022-10-19
• Completion: 2024-12-10
• First posted: 2020-10-23
• Last updated: 2024-12-24

Locations

3 sites across 1 country: Russia